Metabolic plasticity of central carbon metabolism protects mycobacteria

Por Cumming, Bridgette M., Steyn, Adrie J. C.
Publicado no Proc Natl Acad Sci U S A (2015)

Mycobacterium tuberculosis WhiB3: A Novel Iron–Sulfur Cluster Protein That Regulates Redox Homeostasis and Virulence

Por Saini, Vikram, Farhana, Aisha, Steyn, Adrie J.C.
Publicado em 2012

Dissecting virulence pathways of Mycobacterium tuberculosis through protein–protein association

Por Singh, Amit, Mai, Deborah, Kumar, Ashwani, Steyn, Adrie J. C.
Publicado em 2006

Environmental Heme-Based Sensor Proteins: Implications for Understanding Bacterial Pathogenesis

Por Farhana, Aisha, Saini, Vikram, Kumar, Ashwani, Lancaster, Jack R., Steyn, Adrie J.C.
Publicado em 2012

Redox homeostasis in mycobacteria: the key to tuberculosis control?

Por Kumar, Ashwani, Farhana, Aisha, Guidry, Loni, Saini, Vikram, Hondalus, Mary, Steyn, Adrie J.C.
Publicado em 2011

Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor

Por Kumar, Ashwani, Toledo, Jose C., Patel, Rakesh P., Lancaster, Jack R., Steyn, Adrie J. C.
Publicado em 2007

A Screen to Identify Small Molecule Inhibitors of Protein–Protein Interactions in Mycobacteria

Por Mai, Deborah, Jones, Jennifer, Rodgers, John W., Hartman, John L., Kutsch, Olaf, Steyn, Adrie J.C.
Publicado em 2011

Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth

Por Steyn, Adrie J. C., Collins, Desmond M., Hondalus, Mary K., Jacobs, William R., Kawakami, R. Pamela, Bloom, Barry R.
Publicado em 2002

Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response

Por Singh, Amit, Crossman, David K., Mai, Deborah, Guidry, Loni, Voskuil, Martin I., Renfrow, Matthew B., Steyn, Adrie J. C.
Publicado em 2009

Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity

Por Richard-Greenblatt, Melissa, Bach, Horacio, Adamson, John, Peña-Diaz, Sandra, Li, Wu, Steyn, Adrie J. C., Av-Gay, Yossef
Publicado no J Biol Chem (2015)

Heme Oxygenase-1-derived Carbon Monoxide Induces the Mycobacterium tuberculosis Dormancy Regulon

Por Kumar, Ashwani, Deshane, Jessy S., Crossman, David K., Bolisetty, Subhashini, Yan, Bo-Shiun, Kramnik, Igor, Agarwal, Anupam, Steyn, Adrie J. C.
Publicado em 2008

Conservation of Structure and Protein-Protein Interactions Mediated by the Secreted Mycobacterial Proteins EsxA, EsxB, and EspA

Por Callahan, Brian, Nguyen, Kiet, Collins, Alissa, Valdes, Kayla, Caplow, Michael, Crossman, David K., Steyn, Adrie J. C., Eisele, Leslie, Derbyshire, Keith M.
Publicado em 2010

Mycobacterium tuberculosis WhiB3 responds to O(2) and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival

Por Singh, Amit, Guidry, Loni, Narasimhulu, K. V., Mai, Deborah, Trombley, John, Redding, Kevin E., Giles, Gregory I., Lancaster, Jack R., Steyn, Adrie J. C.
Publicado em 2007

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Por Lamprecht, Dirk A., Finin, Peter M., Rahman, Md. Aejazur, Cumming, Bridgette M., Russell, Shannon L., Jonnala, Surendranadha R., Adamson, John H., Steyn, Adrie J. C.
Publicado no Nat Commun (2016)

Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo

Por Chawla, Manbeena, Parikh, Pankti, Saxena, Alka, Munshi, MohamedHusen, Mehta, Mansi, Mai, Deborah, Srivastava, Anup K, Narasimhulu, K V, Redding, Kevin E, Vashi, Nimi, Kumar, Dhiraj, Steyn, Adrie J C, Singh, Amit
Publicado em 2012

Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis

Por Saini, Vikram, Cumming, Bridgette M., Guidry, Loni, Lamprecht, Dirk, Adamson, John H., Reddy, Vineel P., Chinta, Krishna C., Mazorodzo, James, Glasgow, Joel N., Richard-Greenblatt, Melissa, Gomez-Velasco, Anaximandro, Bach, Horacio, Av-Gay, Yossef, Eoh, Hyungjin, Rhee, Kyu, Steyn, Adrie J.C.
Publicado no Cell Rep (2016)

S100A8/A9 Proteins Mediate Neutrophilic Inflammation and Lung Pathology during Tuberculosis

Por Gopal, Radha, Monin, Leticia, Torres, Diana, Slight, Samantha, Mehra, Smriti, McKenna, Kyle C., Fallert Junecko, Beth A., Reinhart, Todd A., Kolls, Jay, Báez-Saldaña, Renata, Cruz-Lagunas, Alfredo, Rodríguez-Reyna, Tatiana S., Kumar, Nathella Pavan, Tessier, Phillipe, Roth, Johannes, Selman, Moisés, Becerril-Villanueva, Enrique, Baquera-Heredia, Javier, Cumming, Bridgette, Kasprowicz, Victoria O., Steyn, Adrie J. C., Babu, Subash, Kaushal, Deepak, Zúñiga, Joaquín, Vogl, Thomas, Rangel-Moreno, Javier, Khader, Shabaana A.
Publicado em 2013