Mycobacterium tuberculosis WhiB3 responds to O(2) and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival

A fundamental challenge in the redox biology of Mycobacterium tuberculosis (Mtb) is to understand the mechanisms involved in sensing redox signals such as oxygen (O(2)), nitric oxide (NO), and nutrient depletion, which are thought to play a crucial role in persistence. Here we show that Mtb WhiB3 re...

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Bibliografiske detaljer
Main Authors: Singh, Amit, Guidry, Loni, Narasimhulu, K. V., Mai, Deborah, Trombley, John, Redding, Kevin E., Giles, Gregory I., Lancaster, Jack R., Steyn, Adrie J. C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906726/
https://ncbi.nlm.nih.gov/pubmed/17609386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700490104
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