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Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response

The metabolic events associated with maintaining redox homeostasis in Mycobacterium tuberculosis (Mtb) during infection are poorly understood. Here, we discovered a novel redox switching mechanism by which Mtb WhiB3 under defined oxidizing and reducing conditions differentially modulates the assimil...

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Detalhes bibliográficos
Main Authors: Singh, Amit, Crossman, David K., Mai, Deborah, Guidry, Loni, Voskuil, Martin I., Renfrow, Matthew B., Steyn, Adrie J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718811/
https://ncbi.nlm.nih.gov/pubmed/19680450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000545
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