Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response

The metabolic events associated with maintaining redox homeostasis in Mycobacterium tuberculosis (Mtb) during infection are poorly understood. Here, we discovered a novel redox switching mechanism by which Mtb WhiB3 under defined oxidizing and reducing conditions differentially modulates the assimil...

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Bibliographic Details
Main Authors: Singh, Amit, Crossman, David K., Mai, Deborah, Guidry, Loni, Voskuil, Martin I., Renfrow, Matthew B., Steyn, Adrie J. C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718811/
https://ncbi.nlm.nih.gov/pubmed/19680450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000545
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