Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response

The metabolic events associated with maintaining redox homeostasis in Mycobacterium tuberculosis (Mtb) during infection are poorly understood. Here, we discovered a novel redox switching mechanism by which Mtb WhiB3 under defined oxidizing and reducing conditions differentially modulates the assimil...

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Main Authors: Singh, Amit, Crossman, David K., Mai, Deborah, Guidry, Loni, Voskuil, Martin I., Renfrow, Matthew B., Steyn, Adrie J. C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718811/
https://ncbi.nlm.nih.gov/pubmed/19680450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000545
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