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Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth

Previous work established that the principal sigma factor (RpoV) of virulent Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex, restores virulence to an attenuated strain containing a point mutation (Arg-515→His) in the 4.2 domain of RpoV. We used the 4.2 domain of RpoV as bait...

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Detalhes bibliográficos
Main Authors: Steyn, Adrie J. C., Collins, Desmond M., Hondalus, Mary K., Jacobs, William R., Kawakami, R. Pamela, Bloom, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122487/
https://ncbi.nlm.nih.gov/pubmed/11880648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052705399
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