Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells

Por Mendum, Tom A, Wu, Huihai, Kierzek, Andrzej M, Stewart, Graham R
Publicado no BMC Genomics (2015)

Mycobacterial Mutants with Defective Control of Phagosomal Acidification

Por Stewart, Graham R, Patel, Janisha, Robertson, Brian D, Rae, Aaron, Young, Douglas B
Publicado em 2005

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

Por Beste, Dany J. V., Espasa, Mateus, Bonde, Bhushan, Kierzek, Andrzej M., Stewart, Graham R., McFadden, Johnjoe
Publicado em 2009

The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence

Por Butler, Rachel E., Brodin, Priscille, Jang, Jichan, Jang, Mi-Seon, Robertson, Brian D., Gicquel, Brigitte, Stewart, Graham R.
Publicado em 2012

The Heat Shock Response of Mycobacterium Tuberculosis: Linking Gene Expression, Immunology and Pathogenesis

Por Stewart, Graham R., Wernisch, Lorenz, Stabler, Richard, Mangan, Joseph A., Hinds, Jason, Laing, Ken G., Butcher, Philip D., Young, Douglas B.
Publicado em 2002

Tetracycline-inducible gene regulation in mycobacteria

Por Blokpoel, Marian C. J., Murphy, Helen N., O'Toole, Ronan, Wiles, Siouxsie, Runn, Ellen S. C., Stewart, Graham R., Young, Douglas B., Robertson, Brian D.
Publicado em 2005

A mutant of Mycobacterium tuberculosis lacking the 19-kilodalton lipoprotein Rv3763 is highly attenuated in vivo but retains potent vaccinogenic properties

Por Henao-Tamayo, Marcela, Junqueira-Kipnis, Ana Paula, Ordway, Diane, Gonzales-Juarrero, Mercedes, Stewart, Graham R., Young, Douglas B., Wilkinson, Robert J., Basaraba, Randall J., Orme, Ian M.
Publicado em 2007

OX40 Ligand Fusion Protein Delivered Simultaneously With the BCG Vaccine Provides Superior Protection Against Murine Mycobacterium tuberculosis Infection

Por Snelgrove, Robert J., Cornere, Megan M., Edwards, Lorna, Dagg, Belinda, Keeble, James, Rodgers, Angela, Lyonga, Daphne E., Stewart, Graham R., Young, Douglas B., Walker, Barry, Hussell, Tracy
Publicado em 2012

Effect of Deletion or Overexpression of the 19-Kilodalton Lipoprotein Rv3763 on the Innate Response to Mycobacterium tuberculosis

Por Stewart, Graham R., Wilkinson, Katalin A., Newton, Sandra M., Sullivan, Susan M., Neyrolles, Olivier, Wain, John R., Patel, Janisha, Pool, Kara-Lee, Young, Douglas B., Wilkinson, Robert J.
Publicado em 2005

Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis

Por Wilkinson, Katalin A, Newton, Sandra M, Stewart, Graham R, Martineau, Adrian R, Patel, Janisha, Sullivan, Susan M, Herrmann, Jean-Louis, Neyrolles, Olivier, Young, Douglas B, Wilkinson, Robert J
Publicado em 2009

The Non-structural Protein 5 and Matrix Protein Are Antigenic Targets of T Cell Immunity to Genotype 1 Porcine Reproductive and Respiratory Syndrome Viruses

Por Mokhtar, Helen, Pedrera, Miriam, Frossard, Jean-Pierre, Biffar, Lucia, Hammer, Sabine E., Kvisgaard, Lise K., Larsen, Lars E., Stewart, Graham R., Somavarapu, Satyanarayana, Steinbach, Falko, Graham, Simon P.
Publicado no Front Immunol (2016)

Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens

Por Riitho, Victor, Walters, Adam A., Somavarapu, Satyanarayana, Lamp, Benjamin, Rümenapf, Till, Krey, Thomas, Rey, Felix A., Oviedo-Orta, Ernesto, Stewart, Graham R., Locker, Nicolas, Steinbach, Falko, Graham, Simon P.
Publicado no Sci Rep (2017)

Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic

Por Mendum, Tom A, Schuenemann, Verena J, Roffey, Simon, Taylor, G Michael, Wu, Huihai, Singh, Pushpendra, Tucker, Katie, Hinds, Jason, Cole, Stewart T, Kierzek, Andrzej M, Nieselt, Kay, Krause, Johannes, Stewart, Graham R
Publicado no BMC Genomics (2014)

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

Por Pitarque, Sylvain, Herrmann, Jean-Louis, Duteyrat, Jean-Luc, Jackson, Mary, Stewart, Graham R., Lecointe, François, Payre, Bruno, Schwartz, Olivier, Young, Douglas B., Marchal, Gilles, Lagrange, Philippe H., Puzo, Germain, Gicquel, Brigitte, Nigou, Jérôme, Neyrolles, Olivier
Publicado em 2005

Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital

Por Taylor, G. Michael, Tucker, Katie, Butler, Rachel, Pike, Alistair W. G., Lewis, Jamie, Roffey, Simon, Marter, Philip, Lee, Oona Y-C, Wu, Houdini H. T., Minnikin, David E., Besra, Gurdyal S., Singh, Pushpendra, Cole, Stewart T., Stewart, Graham R.
Publicado em 2013

Osteological, Biomolecular and Geochemical Examination of an Early Anglo-Saxon Case of Lepromatous Leprosy

Por Inskip, Sarah A., Taylor, G. Michael, Zakrzewski, Sonia R., Mays, Simon A., Pike, Alistair W. G., Llewellyn, Gareth, Williams, Christopher M., Lee, Oona Y-C, Wu, Houdini H. T., Minnikin, David E., Besra, Gurdyal S., Stewart, Graham R.
Publicado no PLoS One (2015)

MUFINS: multi-formalism interaction network simulator

Por Wu, Huihai, von Kamp, Axel, Leoncikas, Vytautas, Mori, Wataru, Sahin, Nilgun, Gevorgyan, Albert, Linley, Catherine, Grabowski, Marek, Mannan, Ahmad A, Stoy, Nicholas, Stewart, Graham R, Ward, Lara T, Lewis, David J M, Sroka, Jacek, Matsuno, Hiroshi, Klamt, Steffen, Westerhoff, Hans V, McFadden, Johnjoe, Plant, Nicholas J, Kierzek, Andrzej M
Publicado no NPJ Syst Biol Appl (2016)

High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

Por Brodin, Priscille, Poquet, Yannick, Levillain, Florence, Peguillet, Isabelle, Larrouy-Maumus, Gerald, Gilleron, Martine, Ewann, Fanny, Christophe, Thierry, Fenistein, Denis, Jang, Jichan, Jang, Mi-Seon, Park, Sei-Jin, Rauzier, Jean, Carralot, Jean-Philippe, Shrimpton, Rachel, Genovesio, Auguste, Gonzalo-Asensio, Jesus A., Puzo, Germain, Martin, Carlos, Brosch, Roland, Stewart, Graham R., Gicquel, Brigitte, Neyrolles, Olivier
Publicado em 2010

A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion

Por Newton, Sandra M., Smith, Rebecca J., Wilkinson, Katalin A., Nicol, Mark P., Garton, Natalie J., Staples, Karl J., Stewart, Graham R., Wain, John R., Martineau, Adrian R., Fandrich, Sarah, Smallie, Timothy, Foxwell, Brian, Al-Obaidi, Ahmed, Shafi, Jamila, Rajakumar, Kumar, Kampmann, Beate, Andrew, Peter W., Ziegler-Heitbrock, Loems, Barer, Michael R., Wilkinson, Robert J.
Publicado em 2006