High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

The ability of the tubercle bacillus to arrest phagosome maturation is considered one major mechanism that allows its survival within host macrophages. To identify mycobacterial genes involved in this process, we developed a high throughput phenotypic cell-based assay enabling individual sub-cellula...

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Detalhes bibliográficos
Main Authors: Brodin, Priscille, Poquet, Yannick, Levillain, Florence, Peguillet, Isabelle, Larrouy-Maumus, Gerald, Gilleron, Martine, Ewann, Fanny, Christophe, Thierry, Fenistein, Denis, Jang, Jichan, Jang, Mi-Seon, Park, Sei-Jin, Rauzier, Jean, Carralot, Jean-Philippe, Shrimpton, Rachel, Genovesio, Auguste, Gonzalo-Asensio, Jesus A., Puzo, Germain, Martin, Carlos, Brosch, Roland, Stewart, Graham R., Gicquel, Brigitte, Neyrolles, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936551/
https://ncbi.nlm.nih.gov/pubmed/20844580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001100
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