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Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

Mycobacterium tuberculosis (Mtb) uses efficient strategies to evade the eradication by professional phagocytes, involving—as recently confirmed—escape from phagosomal confinement. While Mtb determinants, such as the ESX-1 type VII secretion system, that contribute to this phenomenon are known, the h...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Simeone, Roxane, Sayes, Fadel, Song, Okryul, Gröschel, Matthias I., Brodin, Priscille, Brosch, Roland, Majlessi, Laleh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450080/
https://ncbi.nlm.nih.gov/pubmed/25658322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004650
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