Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

Mycobacterium tuberculosis (Mtb) uses efficient strategies to evade the eradication by professional phagocytes, involving—as recently confirmed—escape from phagosomal confinement. While Mtb determinants, such as the ESX-1 type VII secretion system, that contribute to this phenomenon are known, the h...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Simeone, Roxane, Sayes, Fadel, Song, Okryul, Gröschel, Matthias I., Brodin, Priscille, Brosch, Roland, Majlessi, Laleh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450080/
https://ncbi.nlm.nih.gov/pubmed/25658322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004650
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