Pharmacotherapy of pulmonary hypertension

Por Humbert, Marc., Evgenov, Oleg V., Stasch, Johannes-Peter.
Publicado em 2013

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

Por Stasch, Johannes-Peter, Pacher, Pál, Evgenov, Oleg V.
Publicado em 2011

Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase

Por Rauch, Kerstin, Stasch, Johannes-Peter, Kaever, Volkhard, Seifert, Roland
Publicado em 2009

Biomarkers in two different animal models of pulmonary arterial hypertension (PAH) under treatment with a cGMP enhancing substance

Por Grupe, Julia, Neumann, Andrea, Stasch, Johannes-Peter, Leineweber, Kirsten
Publicado em 2011

Relaxant effect of BAY 41-2272 and BAY 58-2667 in the gastrointestinal tract of apo-sGC mice

Por Cosyns, Sarah, Stasch, Johannes-Peter, Brouckaert, Peter, Lefebvre, Romain A
Publicado em 2011

Evidence for two catalytic centers and Mn(2+) as physiological cofactor of soluble guanylyl cyclase

Por Beste, Kerstin Yvonne, Stasch, Johannes-Peter, Kaever, Volkhard, Seifert, Roland
Publicado em 2011

Comparison of different vasodilators, endothelin antagonist, PDE5 inhibitior and sGC stimulators, in an animal model of secondary pulmonary hypertension: effects on “desaturation”...

Por Becker, Eva Maria, Stasch, Johannes-Peter, Bechem, Martin, Truebel, Hubert
Publicado em 2011

NO-independent stimulation or activation of soluble guanylyl cyclase during early reperfusion limits infarct size

Por Bice, Justin S., Keim, Yvonne, Stasch, Johannes-Peter, Baxter, Gary F.
Publicado em 2014

Nitric Oxide and Heat Shock Protein 90 Activate Soluble Guanylate Cyclase by Driving Rapid Change in Its Subunit Interactions and Heme Content

Por Ghosh, Arnab, Stasch, Johannes-Peter, Papapetropoulos, Andreas, Stuehr, Dennis J.
Publicado em 2014

cGMP : generators, effectors and therapeutic implications

Por Schmidt, Harald H. H. W., Hofmann, Franz B., Stasch, Johannes-Peter.
Publicado em 2009

Positive inotropic effect of exogenous and endogenous NO in hypertrophic rat hearts

Por Kojda, Georg, Kottenberg, Karin, Stasch, Johannes-Peter, Schrör, Karsten, Noack, Eike
Publicado em 1997

Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studies

Por Stasch, Johannes-Peter, Dembowsky, Klaus, Perzborn, Elisabeth, Stahl, Elke, Schramm, Matthias
Publicado em 2002

Chronic Activation of Heme Free Guanylate Cyclase Leads to Renal Protection in Dahl Salt-Sensitive Rats

Por Hoffmann, Linda S., Kretschmer, Axel, Lawrenz, Bettina, Hocher, Berthold, Stasch, Johannes-Peter
Publicado no PLoS One (2015)

The uremic retention solute p-cresyl sulfate alters NO signal transduction by alteration of the soluble guanylate cyclase redox state

Por Meijers, Björn KI, Meye, Constanze, Stasch, Johannes-Peter, Gross, Peter, Evenepoel, Pieter
Publicado em 2009

Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators

Por Mülsch, Alexander, Bauersachs, Johann, Schäfer, Andreas, Stasch, Johannes-Peter, Kast, Raimund, Busse, Rudi
Publicado em 1997

Pharmacological preconditioning with the guanylate cyclase activator cinaciguat (BAY 58-2667) protects against reperfusion injury after cardiopulmonary bypass

Por Radovits, Tamás, Korkmaz, Sevil, Loganathan, Sivakkanan, Stasch, Johannes-Peter, Karck, Matthias, Szabó, Gábor
Publicado em 2009

Chronic activation of heme free soluble guanylate cyclase leads to cardio-renal protection in experimental hypertension

Por Hoffmann, Linda S, Kretschmer, Axel, Lawrenz, Bettina, Hucke, Andreas, Hocher, Berthold, Stasch, Johannes-Peter
Publicado em 2013

Antihypertrophic actions of NO-independent soluble guanylyl cyclase (sGC) ligands BAY 41-2272 and BAY 58-2667 in vitro

Por Ritchie, Rebecca, Irvine, Jennifer, Love, Jane, Horowitz, John, Stasch, Johannes-Peter, Kemp-Harper, Barbara
Publicado em 2009

Activation of heme-free soluble guanylate cyclase with cinaciguat has beneficial cardiorenal actions when added to furosemide in experimental heart failure

Por Boerrigter, Guido, Costello-Boerrigter, Lisa C, Cataliotti, Alessandro, Stasch, Johannes-Peter, Burnett, John C
Publicado em 2011

Increases survival by apo-sGC activation via post-stroke blood brain barrier stabilisation and anti-inflammation

Por Langhauser, Friedericke, Hauck, Annegret, Radermacher, Kim, Stasch, Johannes-Peter, Kleinschnitz, Christoph, Schmidt, Harald HHW
Publicado em 2013