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Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studies

1. BAY 41-8543 is a novel non-NO-based stimulator of sGC. This study investigates the acute effects of BAY 41-8543 on haemodynamics in anaesthetized rats and dogs, its long-term effects in conscious hypertension rat models and its antiplatelet effects. 2. In anaesthetized dogs, intravenous injection...

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Main Authors: Stasch, Johannes-Peter, Dembowsky, Klaus, Perzborn, Elisabeth, Stahl, Elke, Schramm, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573146/
https://ncbi.nlm.nih.gov/pubmed/11815369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704483
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