Chronic intratracheal application of the soluble guanylyl cyclase stimulator BAY 41-8543 ameliorates experimental pulmonary hypertension

Dysfunction of the NO/sGC/cGMP signaling pathway has been implicated in the pathogenesis of pulmonary hypertension (PH). Therefore, agents stimulating cGMP synthesis via sGC are important therapeutic options for treatment of PH patients. An unwanted effect of this novel class of drugs is their syste...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Amirjanians, Matthieu, Egemnazarov, Bakytbek, Sydykov, Akylbek, Kojonazarov, Baktybek, Brandes, Ralf, Luitel, Himal, Pradhan, Kabita, Stasch, Johannes-Peter, Redlich, Gorden, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein, Schermuly, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444690/
https://ncbi.nlm.nih.gov/pubmed/28410199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16769
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