Chronic intratracheal application of the soluble guanylyl cyclase stimulator BAY 41-8543 ameliorates experimental pulmonary hypertension

Dysfunction of the NO/sGC/cGMP signaling pathway has been implicated in the pathogenesis of pulmonary hypertension (PH). Therefore, agents stimulating cGMP synthesis via sGC are important therapeutic options for treatment of PH patients. An unwanted effect of this novel class of drugs is their syste...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Amirjanians, Matthieu, Egemnazarov, Bakytbek, Sydykov, Akylbek, Kojonazarov, Baktybek, Brandes, Ralf, Luitel, Himal, Pradhan, Kabita, Stasch, Johannes-Peter, Redlich, Gorden, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein, Schermuly, Ralph
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper: Pathology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444690/
https://ncbi.nlm.nih.gov/pubmed/28410199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16769
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