Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

Although the response of the right ventricle (RV) to the increased afterload is an important determinant of the patient outcome, very little is known about the underlying mechanisms. Mast cells have been implicated in the pathogenesis of left ventricular maladaptive remodeling and failure. However,...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Sydykov, Akylbek, Luitel, Himal, Mamazhakypov, Argen, Wygrecka, Malgorzata, Pradhan, Kabita, Pak, Oleg, Petrovic, Aleksandar, Kojonazarov, Baktybek, Weissmann, Norbert, Seeger, Werner, Grimminger, Friedrich, Ghofrani, Hossein Ardeschir, Kosanovic, Djuro, Schermuly, Ralph Theo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729505/
https://ncbi.nlm.nih.gov/pubmed/33265921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239099
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