Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

Although the response of the right ventricle (RV) to the increased afterload is an important determinant of the patient outcome, very little is known about the underlying mechanisms. Mast cells have been implicated in the pathogenesis of left ventricular maladaptive remodeling and failure. However,...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Sydykov, Akylbek, Luitel, Himal, Mamazhakypov, Argen, Wygrecka, Malgorzata, Pradhan, Kabita, Pak, Oleg, Petrovic, Aleksandar, Kojonazarov, Baktybek, Weissmann, Norbert, Seeger, Werner, Grimminger, Friedrich, Ghofrani, Hossein Ardeschir, Kosanovic, Djuro, Schermuly, Ralph Theo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729505/
https://ncbi.nlm.nih.gov/pubmed/33265921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239099
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