Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice

Although the response of the right ventricle (RV) to the increased afterload is an important determinant of the patient outcome, very little is known about the underlying mechanisms. Mast cells have been implicated in the pathogenesis of left ventricular maladaptive remodeling and failure. However,...

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Udgivet i:Int J Mol Sci
Main Authors: Sydykov, Akylbek, Luitel, Himal, Mamazhakypov, Argen, Wygrecka, Malgorzata, Pradhan, Kabita, Pak, Oleg, Petrovic, Aleksandar, Kojonazarov, Baktybek, Weissmann, Norbert, Seeger, Werner, Grimminger, Friedrich, Ghofrani, Hossein Ardeschir, Kosanovic, Djuro, Schermuly, Ralph Theo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729505/
https://ncbi.nlm.nih.gov/pubmed/33265921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239099
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