Pharmacological actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vitro studies

1. BAY 41-8543 is a novel, highly specific and so far the most potent NO-independent stimulator of sGC. Here we report the effects of BAY 41-8543 on the isolated enzyme, endothelial cells, platelets, isolated vessels and Langendorff heart preparation. 2. BAY 41-8543 stimulates the recombinant sGC co...

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Bibliografiska uppgifter
Huvudupphovsmän: Stasch, Johannes-Peter, Alonso-Alija, Cristina, Apeler, Heiner, Dembowsky, Klaus, Feurer, Achim, Minuth, Torsten, Perzborn, Elisabeth, Schramm, Matthias, Straub, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
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Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573147/
https://ncbi.nlm.nih.gov/pubmed/11815368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704484
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