NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272

BACKGROUND: The most important receptor for nitic oxide is the soluble guanylate cyclase (sGC), a heme containing heterodimer. Recently, a pyrazolopyridine derivative BAY 41-2272, structurally related to YC-1, was identified stimulating soluble guanylate cyclase in an NO-independent manner, which re...

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Hlavní autoři: Becker, Eva Maria, Alonso-Alija, Cristina, Apeler, Heiner, Gerzer, Rupert, Minuth, Torsten, Pleiβ, Ulrich, Schmidt, Peter, Schramm, Matthias, Schröder, Henning, Schroeder, Werner, Steinke, Wolfram, Straub, Alexander, Stasch, Johannes-Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2001
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC64637/
https://ncbi.nlm.nih.gov/pubmed/11801189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-1-13
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