DISCOVER: much accomplished, but not yet for all

por Spiegel, Hans M L
Publicado en Lancet (2020)

FEASIBILITY OF RADIOLABELED SMALL MOLECULE PERMEABILITY AS A QUANTITATIVE MEASURE OF MICROBICIDE CANDIDATE TOXICITY

por Coleman, Jenell, Fuchs, Edward, Aung, Wutyi S., Marzinke, Mark A., Bakshi, Rahul P., Spiegel, Hans M.L., Robinson, Jennifer, Hendrix, Craig W.
Publicado en Contraception (2016)

Comparison of the pharmacokinetics and pharmacodynamics of single-dose tenofovir vaginal film and gel formulation (FAME-05)

por Robinson, Jennifer A., Marzinke, Mark A., Fuchs, Edward J., Bakshi, Rahul P., Spiegel, Hans M. L., Coleman, Jenell S., Rohan, Lisa C., Hendrix, Craig W.
Publicado en J Acquir Immune Defic Syndr (2018)

Lower HIV risk among circumcised men who have sex with men in China: Interaction with anal sex role in a cross-sectional study

por Qian, Han-Zhu, Ruan, Yuhua, Liu, Yu, Milam, Douglas F., Spiegel, Hans M .L., Yin, Lu, Li, Dongliang, Shepherd, Bryan E., Shao, Yiming, Vermund, Sten H.
Publicado en J Acquir Immune Defic Syndr (2016)

Cost-Effectiveness of Pre-exposure HIV Prophylaxis During Pregnancy and Breastfeeding in Sub-Saharan Africa

por Price, Joan T., Wheeler, Stephanie B., Stranix-Chibanda, Lynda, Hosek, Sybil G., Watts, D. Heather, Siberry, George K., Spiegel, Hans M. L., Stringer, Jeffrey S., Chi, Benjamin H.
Publicado en J Acquir Immune Defic Syndr (2016)

Predictors of resolution and persistence of renal laboratory abnormalities in Pediatric HIV infection

por Mitchell, Charles D., Chernoff, Miriam C., Seage, George R., Purswani, Murli U., Spiegel, Hans M.L., Zilleruelo, Gaston, Abitbol, Carolyn, Heckman, Barbara, Ponce, Christopher B., Oleske, James M.
Publicado en Pediatr Nephrol (2014)

Comparison of Dapivirine Vaginal Gel and Film Formulation Pharmacokinetics and Pharmacodynamics (FAME 02B)

por Robinson, Jennifer A., Marzinke, Mark A., Bakshi, Rahul P., Fuchs, Edward J., Radebaugh, Christine L., Aung, Wutyi, Spiegel, Hans M.L., Coleman, Jenell S., Rohan, Lisa C., Hendrix, Craig W.
Publicado en AIDS Res Hum Retroviruses (2017)

Small for gestational age: Case definition & guidelines for data collection, analysis, and presentation of maternal immunisation safety data

por Schlaudecker, Elizabeth P., Munoz, Flor M., Bardají, Azucena, Boghossian, Nansi S., Khalil, Asma, Mousa, Hatem, Nesin, Mirjana, Nisar, Muhammad Imran, Pool, Vitali, Spiegel, Hans M.L., Tapia, Milagritos D., Kochhar, Sonali, Black, Steven
Publicado en Vaccine (2017)

FAME‐04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of film and gel formulations of tenofovir

por Bunge, Katherine E, Dezzutti, Charlene S, Hendrix, Craig W, Marzinke, Mark A, Spiegel, Hans M L, Moncla, Bernard J, Schwartz, Jill L, Meyn, Leslie A, Richardson‐Harman, Nicola, Rohan, Lisa C, Hillier, Sharon L
Publicado en J Int AIDS Soc (2018)

Human Immunodeficiency Virus Type 1- and Cytomegalovirus-Specific Cytotoxic T Lymphocytes Can Persist at High Frequency for Prolonged Periods in the Absence of Circulating Periphe...

por Spiegel, Hans M. L., Ogg, Graham S., DeFalcon, Elizabeth, Sheehy, Megan E., Monard, Simon, Haslett, Patrick A. J., Gillespie, Geraldine, Donahoe, Sean M., Pollack, Henry, Borkowsky, William, McMichael, Andrew J., Nixon, Douglas F.
Publicado 2000

Nonlinear pharmacokinetics of high-dose recombinant fusion protein CD4-IgG(2) (PRO 542) observed in HIV-1–infected children

por Fletcher, Courtney V., DeVille, Jaime G., Samson, Pearl M., Moye, John H., Church, Joseph A., Spiegel, Hans M. L., Palumbo, Paul, Fenton, Terence, Smith, M. Elizabeth, Graham, Bobbie, Kraimer, Joyce M., Shearer, William T.
Publicado 2007

Decline in CD4 T lymphocytes with monotherapy bridging strategy for non-adherent adolescents living with HIV infection: Results of the IMPAACT P1094 randomized trial

por Agwu, Allison L., Warshaw, Meredith G., McFarland, Elizabeth J., Siberry, George K., Melvin, Ann J., Wiznia, Andrew A., Fairlie, Lee, Boyd, Sandra, Harding, Paul, Spiegel, Hans M. L., Abrams, Elaine J., Carey, Vincent J.
Publicado en PLoS One (2017)

Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial

por Politch, Joseph A., Cu-Uvin, Susan, Moench, Thomas R., Tashima, Karen T., Marathe, Jai G., Guthrie, Kate M., Cabral, Howard, Nyhuis, Tara, Brennan, Miles, Zeitlin, Larry, Spiegel, Hans M. L., Mayer, Kenneth H., Whaley, Kevin J., Anderson, Deborah J.
Publicado en PLoS Med (2021)

A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unpr...

por Hiruy, Hiwot, Fuchs, Edward J., Marzinke, Mark A., Bakshi, Rahul P., Breakey, Jennifer C., Aung, Wutyi S., Manohar, Madhuri, Yue, Chen, Caffo, Brian S., Du, Yong, Abebe, Kaleab Z., Spiegel, Hans M.L., Rohan, Lisa C., McGowan, Ian, Hendrix, Craig W.
Publicado en AIDS Res Hum Retroviruses (2015)

Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children: An Update

por Graham, Stephen M., Cuevas, Luis E., Jean-Philippe, Patrick, Browning, Renee, Casenghi, Martina, Detjen, Anne K., Gnanashanmugam, Devasena, Hesseling, Anneke C., Kampmann, Beate, Mandalakas, Anna, Marais, Ben J., Schito, Marco, Spiegel, Hans M. L., Starke, Jeffrey R., Worrell, Carol, Zar, Heather J.
Publicado en Clin Infect Dis (2015)

A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis

por Nicol, Mark Patrick, Gnanashanmugam, Devasena, Browning, Renee, Click, Eleanor S., Cuevas, Luis E., Detjen, Anne, Graham, Steve M., Levin, Michael, Makhene, Mamodikoe, Nahid, Payam, Perez-Velez, Carlos M., Reither, Klaus, Song, Rinn, Spiegel, Hans M. L., Worrell, Carol, Zar, Heather J., Walzl, Gerhard
Publicado en Clin Infect Dis (2015)

HIV-Specific Cd8(+) T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function

por Appay, Victor, Nixon, Douglas F., Donahoe, Sean M., Gillespie, Geraldine M.A., Dong, Tao, King, Abigail, Ogg, Graham S., Spiegel, Hans M.L., Conlon, Christopher, Spina, Celsa A., Havlir, Diane V., Richman, Douglas D., Waters, Anele, Easterbrook, Philippa, McMichael, Andrew J., Rowland-Jones, Sarah L.
Publicado 2000

Guideline for collection, analysis and presentation of safety data in clinical trials of vaccines in pregnant women

por Jones, Christine E., Munoz, Flor M., Spiegel, Hans M.L., Heininger, Ulrich, Zuber, Patrick L.F., Edwards, Kathryn M., Lambach, Philipp, Neels, Pieter, Kohl, Katrin S., Gidudu, Jane, Hirschfeld, Steven, Oleske, James M., Khuri-Bulos, Najwa, Bauwens, Jorgen, Eckert, Linda O., Kochhar, Sonali, Bonhoeffer, Jan, Heath, Paul T.
Publicado en Vaccine (2016)

A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study)

por Mcgowan, Ian, Cranston, Ross D., Duffill, Kathryn, Siegel, Aaron, Engstrom, Jarret C., Nikiforov, Alexyi, Jacobson, Cindy, Rehman, Khaja K., Elliott, Julie, Khanukhova, Elena, Abebe, Kaleab, Mauck, Christine, Spiegel, Hans M. L., Dezzutti, Charlene S., Rohan, Lisa C., Marzinke, Mark A., Hiruy, Hiwot, Hendrix, Craig W., Richardson-Harman, Nicola, Anton, Peter A.
Publicado en PLoS One (2015)

A Polymorphism in the Regulatory Region of the CC-Chemokine Receptor 5 Gene Influences Perinatal Transmission of Human Immunodeficiency Virus Type 1 to African-American Infants

por Kostrikis, Leondios G., Neumann, Avidan U., Thomson, Bruce, Korber, Bette T., McHardy, Paul, Karanicolas, Rose, Deutsch, Lisa, Huang, Yaoxing, Lew, Judy F., McIntosh, Kenneth, Pollack, Henry, Borkowsky, William, Spiegel, Hans M. L., Palumbo, Paul, Oleske, James, Bardeguez, Arlene, Luzuriaga, Katherine, Sullivan, John, Wolinsky, Steven M., Koup, Richard A., Ho, David D., Moore, John P.
Publicado 1999