Human Immunodeficiency Virus Type 1- and Cytomegalovirus-Specific Cytotoxic T Lymphocytes Can Persist at High Frequency for Prolonged Periods in the Absence of Circulating Peripheral CD4(+) T Cells

CD4(+) T cells are thought to be critical in the maintenance of virus-specific CD8(+) cytotoxic T-cell (CTL) responses. In human immunodeficiency virus type 1 (HIV-1) infection, a selective decline in HIV-1-specific CTL as the CD4(+) T-cell count decreases has been reported. Using HLA-peptide tetram...

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書誌詳細

出版年:	J Virol
主要な著者:	Spiegel, Hans M. L., Ogg, Graham S., DeFalcon, Elizabeth, Sheehy, Megan E., Monard, Simon, Haslett, Patrick A. J., Gillespie, Geraldine, Donahoe, Sean M., Pollack, Henry, Borkowsky, William, McMichael, Andrew J., Nixon, Douglas F.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2000
主題:	Pathogenesis and Immunity
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10623767/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.2.1018-1022.2000
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