A Monomeric Variant of Insulin Degrading Enzyme (IDE) Loses Its Regulatory Properties

Por Song, Eun Suk, Rodgers, David W., Hersh, Louis B.
Publicado em 2010

Mixed Dimers of Insulin-degrading Enzyme Reveal a Cis Activation Mechanism

Por Song, Eun Suk, Rodgers, David W., Hersh, Louis B.
Publicado em 2011

Proteolytic Fragments of Insulysin (IDE) Retain Substrate Binding, But Lose Allosteric Regulation

Por Song, Eun Suk, Cady, Clint, Fried, Michael G., Hersh, Louis B.
Publicado em 2006

Anion Activation Site of Insulin-degrading Enzyme

Por Noinaj, Nicholas, Song, Eun Suk, Bhasin, Sonia, Alper, Benjamin J., Schmidt, Walter K., Hersh, Louis B., Rodgers, David W.
Publicado em 2012

Cysteine 904 Is Required for Maximal Insulin Degrading Enzyme Activity and Polyanion Activation

Por Song, Eun Suk, Melikishvili, Manana, Fried, Michael G., Juliano, Maria A., Juliano, Luiz, Rodgers, David W., Hersh, Louis B.
Publicado em 2012

Identification of the Allosteric Regulatory Site of Insulysin

Por Noinaj, Nicholas, Bhasin, Sonia K., Song, Eun Suk, Scoggin, Kirsten E., Juliano, Maria A., Juliano, Luiz, Hersh, Louis B., Rodgers, David W.
Publicado em 2011

An Extended Polyanion Activation Surface in Insulin Degrading Enzyme

Por Song, Eun Suk, Ozbil, Mehmet, Zhang, Tingting, Sheetz, Michael, Lee, David, Tran, Danny, Li, Sheng, Prabhakar, Rajeev, Hersh, Louis B., Rodgers, David W.
Publicado no PLoS One (2015)

In vitro and in vivo degradation of Aβ peptide by peptidases coupled to erythrocytes

Por Liu, Yinxing, Guan, Hanjun, Beckett, Tina L., Juliano, Maria Aparecida, Juliano, Luiz, Song, Eun Suk, Chow, K. Martin, Murphy, M. Paul, Hersh, Louis B.
Publicado em 2007

Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to endosomes

Por Song, Eun Suk, Jang, HyeIn, Guo, Hou-Fu, Juliano, Maria A., Juliano, Luiz, Morris, Andrew J., Galperin, Emilia, Rodgers, David W., Hersh, Louis B.
Publicado no Proc Natl Acad Sci U S A (2017)

Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia

Por Niedowicz, Dana M, Reeves, Valerie L, Platt, Thomas L, Kohler, Katharina, Beckett, Tina L, Powell, David K, Lee, Tiffany L, Sexton, Travis R, Song, Eun Suk, Brewer, Lawrence D, Latimer, Caitlin S, Kraner, Susan D, Larson, Kara L, Ozcan, Sabire, Norris, Christopher M, Hersh, Louis B, Porter, Nada M, Wilcock, Donna M, Murphy, Michael Paul
Publicado no Acta Neuropathol Commun (2014)