Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI

Por Rivero, Francisco, Illenberger, Daria, Somesh, Baggavalli P., Dislich, Heidrun, Adam, Nicola, Meyer, Ann-Kathrin
Publicado em 2002

RacG Regulates Morphology, Phagocytosis, and Chemotaxis

Por Somesh, Baggavalli P., Vlahou, Georgia, Iijima, Miho, Insall, Robert H., Devreotes, Peter, Rivero, Francisco
Publicado em 2006

A novel GPR40 agonist, CNX-011-67, suppresses glucagon secretion in pancreatic islets under chronic glucolipotoxic conditions in vitro

Por Verma, Mahesh Kumar, Biswas, Sanghamitra, Chandravanshi, Bhawna, Neelima, Korrapati, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado em 2014

Integrated analysis of chronic lipotoxicity on muscle metabolism and stress and its reversal by antioxidants

Por Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Smitha, Rachapalli, Neelima, Korrapati, Pallavi, Puttrevana M, Reddy, Madhusudhan, Poornima, Jayaram, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado em 2014

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

Por Harreman, Michelle, Taschner, Michael, Sigurdsson, Stefan, Anindya, Roy, Reid, James, Somesh, Baggavalli, Kong, Stephanie E., Banks, Charles A. S., Conaway, Ronald C., Conaway, Joan W., Svejstrup, Jesper Q.
Publicado em 2009

Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress

Por Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Neelima, Korrapati, Pawar, Niketa, Sandhya, Kandoor, Poornima, Jayaram, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Pallavi, Puttrevana M, Oommen, Anup M, Somesh, Baggavalli P, Jagannath, Madanahalli R
Publicado em 2014

Activation of GPR40 attenuates chronic inflammation induced impact on pancreatic β-cells health and function

Por Verma, Mahesh Kumar, Sadasivuni, Manoj Kumar, Yateesh, Aggunda N, Neelima, Korrapati, Mrudula, Srikanth, Reddy, Madhusudhan, Smitha, Rachapalli, Biswas, Sanghamitra, Chandravanshi, Bhawna, Pallavi, Puttrevana M, Oommen, Anup M, Jagannath, Madanahalli R, Somesh, Baggavalli B
Publicado em 2014

CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients

Por Sunil, Venkategowda, Verma, Mahesh Kumar, Oommen, Anup M, Sadasivuni, Manojkumar, Singh, Jaideep, Vijayraghav, Dasarahalli N, Chandravanshi, Bhawna, Shetty, Jayalaxmi, Biswas, Sanghamitra, Dandu, Anilkumar, Moolemath, Yoganand, Venkataranganna, Marikunte V, Somesh, Baggavalli P, Jagannath, Madanahalli R
Publicado em 2014

Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity

Por Somesh, Baggavalli P, Verma, Mahesh Kumar, Sadasivuni, Manoj Kumar, Mammen-Oommen, Anup, Biswas, Sanghamitra, Shilpa, Pavagada C, Reddy, Ashok Kumar, Yateesh, Aggunda N, Pallavi, Puttrevana M, Nethra, Siddaraju, Smitha, Rachapalli, Neelima, Korrapati, Narayanan, Usha, Jagannath, Madanahalli R
Publicado em 2013

Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats

Por Gowda, Nagesh, Dandu, Anilkumar, Singh, Jaideep, Biswas, Sanghamitra, Raghav, Vijaya, Lakshmi, Mudigere N, Shilpa, Pavagada C, Sunil, Venkategowda, Reddy, Ashokkumar, Sadasivuni, Manojkumar, Aparna, Kumaraswamy, Verma, Mahesh Kumar, Moolemath, Yoganand, Anup, Mammen O, Venkataranganna, Marikunte V, Somesh, Baggavalli P, Jagannath, Madanahalli R
Publicado em 2013

CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db...

Por Anil, Tharappel M, Harish, Chandrashekaran, Lakshmi, Mudigere N, Harsha, KrishnaReddy, Onkaramurthy, Mallappa, Sathish Kumar, Venkatesh, Shree, Nitya, Geetha, Venkatachalaiah, Balamurali, Gundalmandikal V, Gopala, Aralakuppe S, Madhusudhan Reddy, Bobbili, Govind, Madabosse K, Anup, Mammen O, Moolemath, Yoganand, Venkataranganna, Marikunte V, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado em 2014

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potentia...

Por Anil, Tharappel M, Dandu, Anilkumar, Harsha, KrishnaReddy, Singh, Jaideep, Shree, Nitya, Kumar, Venkatesh Satish, Lakshmi, Mudigere N, Sunil, Venkategowda, Harish, Chandrashekaran, Balamurali, Gundalmandikal V, Naveen Kumar, Baisani S, Gopala, Aralakuppe S, Pratibha, Shivakumar, Sadasivuni, ManojKumar, Anup, Mammen O, Moolemath, Yoganand, Venkataranganna, Marikunte V, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado em 2014

CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridem...

Por Sadasivuni, Manoj Kumar, Reddy, Bobbili Madhusudhan, Singh, Jaideep, Anup, Mammen O, Sunil, Venkategowda, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Chacko, Suni K, Pooja, Talanki Lokesh, Dandu, Anilkumar, Harish, Chandrashekaran, Gopala, Aralakuppe S, Pratibha, Shivakumar, Naveenkumar, Baisani S, Pallavi, Puttrevana M, Verma, Mahesh Kumar, Moolemath, Yoganand, Somesh, Baggavalli P, Venkataranganna, Marikunte V, Jagannath, Madanahalli R
Publicado em 2014