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Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI

Rho GDP-dissociation inhibitors (RhoGDIs) modulate the cycling of Rho GTPases between active GTP-bound and inactive GDP-bound states. We identified two RhoGDI homologues in Dictyostelium. GDI1 shares 51–58% similarity to RhoGDIs from diverse species. GDI2 is more divergent (40–44% similarity) and la...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Rivero, Francisco, Illenberger, Daria, Somesh, Baggavalli P., Dislich, Heidrun, Adam, Nicola, Meyer, Ann-Kathrin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126189/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf449
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