The Normal Synovium

le Smith, Malcolm D
Foilsithe 2011

Utility of arthroscopic guided synovial biopsy in understanding synovial tissue pathology in health and disease states

le Wechalekar, Mihir D, Smith, Malcolm D
Foilsithe 2014

Biologic Agents—A Panacea for Inflammatory Arthritis or Not?

le Ninan, J., Smith, Malcolm D., Dugar, M., O'Brien, Karen, Ahern, Michael
Foilsithe 2009

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

le Crotti, Tania N, Dharmapatni, Anak ASSK, Alias, Ekram, Zannettino, Andrew CW, Smith, Malcolm D, Haynes, David R
Foilsithe 2012

The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice

le Dharmapatni, Anak A. S. S. K., Cantley, Melissa D., Marino, Victor, Perilli, Egon, Crotti, Tania N., Smith, Malcolm D., Haynes, David R.
Foilsithe in Mediators Inflamm (2015)

Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways

le Walsh, Alice M., Wechalekar, Mihir D., Guo, Yanxia, Yin, Xuefeng, Weedon, Helen, Proudman, Susanna M., Smith, Malcolm D., Nagpal, Sunil
Foilsithe in PLoS One (2017)

The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)

le Kraan, Maarten C, Patel, Dhavalkumar D, Haringman, Jasper J, Smith, Malcolm D, Weedon, Helen, Ahern, Michael J, Breedveld, Ferdinand C, Tak, Paul P
Foilsithe 2001

Effects of Low-Dose Prednisolone on Hepatic and Peripheral Insulin Sensitivity, Insulin Secretion, and Abdominal Adiposity in Patients With Inflammatory Rheumatologic Disease

le Petersons, Carolyn J., Mangelsdorf, Brenda L., Jenkins, Arthur B., Poljak, Anne, Smith, Malcolm D., Greenfield, Jerry R., Thompson, Campbell H., Burt, Morton G.
Foilsithe 2013

Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy

le Murray-Brown, William, Wilsdon, Tom D, Weedon, Helen, Proudman, Susanna, Sukumaran, Shawgi, Klebe, Sonja, Walker, Jennifer G, Smith, Malcolm D, Wechalekar, Mihir D
Foilsithe in J Immunother Cancer (2020)

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

le Dharmapatni, Anak ASSK, Smith, Malcolm D, Findlay, David M, Holding, Christopher A, Evdokiou, Andreas, Ahern, Michael J, Weedon, Helen, Chen, Paul, Screaton, Gavin, Xu, Xiao N, Haynes, David R
Foilsithe 2009

Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations

le Ngo, Doan TM, Stafford, Irene, Sverdlov, Aaron L, Qi, Weier, Wuttke, Ronald D, Zhang, Yuan, Kelly, Darren J, Weedon, Helen, Smith, Malcolm D, Kennedy, Jennifer A, Horowitz, John D
Foilsithe 2011

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

le Dharmapatni, Anak ASSK, Smith, Malcolm D, Crotti, Tania N, Holding, Christopher A, Vincent, Cristina, Weedon, Helen M, Zannettino, Andrew CW, Zheng, Timothy S, Findlay, David M, Atkins, Gerald J, Haynes, David R
Foilsithe 2011

Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with r...

le Hollis-Moffatt, Jade E, Chen-Xu, Michael, Topless, Ruth, Dalbeth, Nicola, Gow, Peter J, Harrison, Andrew A, Highton, John, Jones, Peter BB, Nissen, Michael, Smith, Malcolm D, van Rij, Andre, Jones, Gregory T, Stamp, Lisa K, Merriman, Tony R
Foilsithe 2010

PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis

le Lester, Susan, Hewitt, Alex W, Ruediger, Carlee D, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael D, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey O, Merriman, Tony R, Shenstone, Bain, Smith, Malcolm D, Rischmueller, Maureen, Brown, Matthew A, Hill, Catherine L
Foilsithe in RMD Open (2016)

Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus

le Cole, Suzanne, Walsh, Alice, Yin, Xuefeng, Wechalekar, Mihir D., Smith, Malcolm D., Proudman, Susanna M., Veale, Douglas J., Fearon, Ursula, Pitzalis, Costantino, Humby, Frances, Bombardieri, Michele, Axel, Amy, Adams, Homer, Chiu, Christopher, Sharp, Michael, Alvarez, John, Anderson, Ian, Madakamutil, Loui, Nagpal, Sunil, Guo, Yanxia
Foilsithe in Arthritis Res Ther (2018)

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

le Guo, Yanxia, Walsh, Alice M., Canavan, Mary, Wechalekar, Mihir D., Cole, Suzanne, Yin, Xuefeng, Scott, Brittney, Loza, Mathew, Orr, Carl, McGarry, Trudy, Bombardieri, Michele, Humby, Frances, Proudman, Susanna M., Pitzalis, Costantino, Smith, Malcolm D., Friedman, Joshua R., Anderson, Ian, Madakamutil, Loui, Veale, Douglas J., Fearon, Ursula, Nagpal, Sunil
Foilsithe in PLoS One (2018)

Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout

le Rasheed, Humaira, Phipps-Green, Amanda J., Topless, Ruth, Smith, Malcolm D., Hill, Catherine, Lester, Susan, Rischmueller, Maureen, Janssen, Matthijs, Jansen, Timothy L., Joosten, Leo A., Radstake, Timothy R., Riches, Philip L., Tausche, Anne-Kathrin, Lioté, Frederic, So, Alexander, van Rij, Andre, Jones, Gregory T., McCormick, Sally P., Harrison, Andrew A., Stamp, Lisa K., Dalbeth, Nicola, Merriman, Tony R.
Foilsithe in Rheumatology (Oxford) (2016)