Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy

BACKGROUND: Immune checkpoint inhibitors (ICIs) are associated with rheumatic and musculoskeletal immune-related adverse events (irAEs) in 5%–20% of patients. Currently, patients refractory to corticosteroids and conventional disease-modifying antirheumatic drugs (cDMARD) are treated with biological...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Murray-Brown, William, Wilsdon, Tom D, Weedon, Helen, Proudman, Susanna, Sukumaran, Shawgi, Klebe, Sonja, Walker, Jennifer G, Smith, Malcolm D, Wechalekar, Mihir D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311067/
https://ncbi.nlm.nih.gov/pubmed/32571993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000281
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