The Normal Synovium

Por Smith, Malcolm D
Publicado em 2011

Utility of arthroscopic guided synovial biopsy in understanding synovial tissue pathology in health and disease states

Por Wechalekar, Mihir D, Smith, Malcolm D
Publicado em 2014

Biologic Agents—A Panacea for Inflammatory Arthritis or Not?

Por Ninan, J., Smith, Malcolm D., Dugar, M., O'Brien, Karen, Ahern, Michael
Publicado em 2009

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

Por Crotti, Tania N, Dharmapatni, Anak ASSK, Alias, Ekram, Zannettino, Andrew CW, Smith, Malcolm D, Haynes, David R
Publicado em 2012

The X-Linked Inhibitor of Apoptosis Protein Inhibitor Embelin Suppresses Inflammation and Bone Erosion in Collagen Antibody Induced Arthritis Mice

Por Dharmapatni, Anak A. S. S. K., Cantley, Melissa D., Marino, Victor, Perilli, Egon, Crotti, Tania N., Smith, Malcolm D., Haynes, David R.
Publicado no Mediators Inflamm (2015)

Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways

Por Walsh, Alice M., Wechalekar, Mihir D., Guo, Yanxia, Yin, Xuefeng, Weedon, Helen, Proudman, Susanna M., Smith, Malcolm D., Nagpal, Sunil
Publicado no PLoS One (2017)

The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)

Por Kraan, Maarten C, Patel, Dhavalkumar D, Haringman, Jasper J, Smith, Malcolm D, Weedon, Helen, Ahern, Michael J, Breedveld, Ferdinand C, Tak, Paul P
Publicado em 2001

Effects of Low-Dose Prednisolone on Hepatic and Peripheral Insulin Sensitivity, Insulin Secretion, and Abdominal Adiposity in Patients With Inflammatory Rheumatologic Disease

Por Petersons, Carolyn J., Mangelsdorf, Brenda L., Jenkins, Arthur B., Poljak, Anne, Smith, Malcolm D., Greenfield, Jerry R., Thompson, Campbell H., Burt, Morton G.
Publicado em 2013

Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy

Por Murray-Brown, William, Wilsdon, Tom D, Weedon, Helen, Proudman, Susanna, Sukumaran, Shawgi, Klebe, Sonja, Walker, Jennifer G, Smith, Malcolm D, Wechalekar, Mihir D
Publicado no J Immunother Cancer (2020)

Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium

Por Dharmapatni, Anak ASSK, Smith, Malcolm D, Findlay, David M, Holding, Christopher A, Evdokiou, Andreas, Ahern, Michael J, Weedon, Helen, Chen, Paul, Screaton, Gavin, Xu, Xiao N, Haynes, David R
Publicado em 2009

Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations

Por Ngo, Doan TM, Stafford, Irene, Sverdlov, Aaron L, Qi, Weier, Wuttke, Ronald D, Zhang, Yuan, Kelly, Darren J, Weedon, Helen, Smith, Malcolm D, Kennedy, Jennifer A, Horowitz, John D
Publicado em 2011

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

Por Dharmapatni, Anak ASSK, Smith, Malcolm D, Crotti, Tania N, Holding, Christopher A, Vincent, Cristina, Weedon, Helen M, Zannettino, Andrew CW, Zheng, Timothy S, Findlay, David M, Atkins, Gerald J, Haynes, David R
Publicado em 2011

Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with r...

Por Hollis-Moffatt, Jade E, Chen-Xu, Michael, Topless, Ruth, Dalbeth, Nicola, Gow, Peter J, Harrison, Andrew A, Highton, John, Jones, Peter BB, Nissen, Michael, Smith, Malcolm D, van Rij, Andre, Jones, Gregory T, Stamp, Lisa K, Merriman, Tony R
Publicado em 2010

PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis

Por Lester, Susan, Hewitt, Alex W, Ruediger, Carlee D, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael D, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey O, Merriman, Tony R, Shenstone, Bain, Smith, Malcolm D, Rischmueller, Maureen, Brown, Matthew A, Hill, Catherine L
Publicado no RMD Open (2016)

Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus

Por Cole, Suzanne, Walsh, Alice, Yin, Xuefeng, Wechalekar, Mihir D., Smith, Malcolm D., Proudman, Susanna M., Veale, Douglas J., Fearon, Ursula, Pitzalis, Costantino, Humby, Frances, Bombardieri, Michele, Axel, Amy, Adams, Homer, Chiu, Christopher, Sharp, Michael, Alvarez, John, Anderson, Ian, Madakamutil, Loui, Nagpal, Sunil, Guo, Yanxia
Publicado no Arthritis Res Ther (2018)

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

Por Guo, Yanxia, Walsh, Alice M., Canavan, Mary, Wechalekar, Mihir D., Cole, Suzanne, Yin, Xuefeng, Scott, Brittney, Loza, Mathew, Orr, Carl, McGarry, Trudy, Bombardieri, Michele, Humby, Frances, Proudman, Susanna M., Pitzalis, Costantino, Smith, Malcolm D., Friedman, Joshua R., Anderson, Ian, Madakamutil, Loui, Veale, Douglas J., Fearon, Ursula, Nagpal, Sunil
Publicado no PLoS One (2018)

Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout

Por Rasheed, Humaira, Phipps-Green, Amanda J., Topless, Ruth, Smith, Malcolm D., Hill, Catherine, Lester, Susan, Rischmueller, Maureen, Janssen, Matthijs, Jansen, Timothy L., Joosten, Leo A., Radstake, Timothy R., Riches, Philip L., Tausche, Anne-Kathrin, Lioté, Frederic, So, Alexander, van Rij, Andre, Jones, Gregory T., McCormick, Sally P., Harrison, Andrew A., Stamp, Lisa K., Dalbeth, Nicola, Merriman, Tony R.
Publicado no Rheumatology (Oxford) (2016)