PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis

Giant cell arteritis (GCA) is one of the commonest forms of vasculitis in the elderly, and may result in blindness and stroke. The pathogenesis of GCA is not understood, although environmental, infectious and genetic risk factors are implicated. One gene of interest is PTPN22, encoding lymphoid prot...

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Dettagli Bibliografici
Pubblicato in:RMD Open
Autori principali: Lester, Susan, Hewitt, Alex W, Ruediger, Carlee D, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael D, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey O, Merriman, Tony R, Shenstone, Bain, Smith, Malcolm D, Rischmueller, Maureen, Brown, Matthew A, Hill, Catherine L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2016
Soggetti:
Vasculitis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838769/
https://ncbi.nlm.nih.gov/pubmed/27110387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000246
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