PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis

Giant cell arteritis (GCA) is one of the commonest forms of vasculitis in the elderly, and may result in blindness and stroke. The pathogenesis of GCA is not understood, although environmental, infectious and genetic risk factors are implicated. One gene of interest is PTPN22, encoding lymphoid prot...

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Detalhes bibliográficos
Publicado no:RMD Open
Main Authors: Lester, Susan, Hewitt, Alex W, Ruediger, Carlee D, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael D, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey O, Merriman, Tony R, Shenstone, Bain, Smith, Malcolm D, Rischmueller, Maureen, Brown, Matthew A, Hill, Catherine L
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Vasculitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838769/
https://ncbi.nlm.nih.gov/pubmed/27110387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000246
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