PTPN22 R620W minor allele is a genetic risk factor for giant cell arteritis

Giant cell arteritis (GCA) is one of the commonest forms of vasculitis in the elderly, and may result in blindness and stroke. The pathogenesis of GCA is not understood, although environmental, infectious and genetic risk factors are implicated. One gene of interest is PTPN22, encoding lymphoid prot...

詳細記述

保存先:
書誌詳細
出版年:RMD Open
主要な著者: Lester, Susan, Hewitt, Alex W, Ruediger, Carlee D, Bradbury, Linda, De Smit, Elisabeth, Wiese, Michael D, Black, Rachel, Harrison, Andrew, Jones, Graeme, Littlejohn, Geoffrey O, Merriman, Tony R, Shenstone, Bain, Smith, Malcolm D, Rischmueller, Maureen, Brown, Matthew A, Hill, Catherine L
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2016
主題:
Vasculitis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838769/
https://ncbi.nlm.nih.gov/pubmed/27110387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000246
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