Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways

OBJECTIVES: This study sought to investigate the genome-wide transcriptional effects of a combination of disease modifying anti-rheumatic drugs (tDMARD; methotrexate, sulfasalazine and hydroxychloroquine) in synovial tissues obtained from early rheumatoid arthritis (RA) patients. While combination D...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Walsh, Alice M., Wechalekar, Mihir D., Guo, Yanxia, Yin, Xuefeng, Weedon, Helen, Proudman, Susanna M., Smith, Malcolm D., Nagpal, Sunil
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580991/
https://ncbi.nlm.nih.gov/pubmed/28863153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183928
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