Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted

par Smit, Johan W, Schinkel, Alfred H, Weert, Betty, Meijer, Dirk K F
Publié 1998

Crosslinked Poly(2-oxazoline)s as “Green” Materials for Electronic Applications

par Fimberger, Martin, Tsekmes, Ioannis-Alexandros, Kochetov, Roman, Smit, Johan J., Wiesbrock, Frank
Publié dans Polymers (Basel) (2015)

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

par Smit, Johan W., Huisman, Maarten T., van Tellingen, Olaf, Wiltshire, Hugh R., Schinkel, Alfred H.
Publié 1999

Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level

par Smit, Johan W, Duin, Erik, Steen, Herman, Oosting, Roelof, Roggeveld, Jan, Meijer, Dirk K F
Publié 1998

Effect of Interfacial Polarization and Water Absorption on the Dielectric Properties of Epoxy-Nanocomposites

par Marx, Philipp, Wanner, Andrea J., Zhang, Zucong, Jin, Huifei, Tsekmes, Ioannis-Alexandros, Smit, Johan J., Kern, Wolfgang, Wiesbrock, Frank
Publié dans Polymers (Basel) (2017)

Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene

par Jonker, Johan W., Wagenaar, Els, Mol, Carla A. A. M., Buitelaar, Marije, Koepsell, Hermann, Smit, Johan W., Schinkel, Alfred H.
Publié 2001

Effect of CYP3A perpetrators on ibrutinib exposure in healthy participants

par de Jong, Jan, Skee, Donna, Murphy, Joe, Sukbuntherng, Juthamas, Hellemans, Peter, Smit, Johan, de Vries, Ronald, Jiao, Juhui James, Snoeys, Jan, Mannaert, Erik
Publié dans Pharmacol Res Perspect (2015)

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

par Sparreboom, Alex, van Asperen, Judith, Mayer, Ulrich, Schinkel, Alfred H., Smit, Johan W., Meijer, Dirk K. F., Borst, Piet, Nooijen, Willem J., Beijnen, Jos H., van Tellingen, Olaf
Publié 1997

Stable isotope‐labelled intravenous microdose for absolute bioavailability and effect of grapefruit juice on ibrutinib in healthy adults

par de Vries, Ronald, Smit, Johan W., Hellemans, Peter, Jiao, James, Murphy, Joseph, Skee, Donna, Snoeys, Jan, Sukbuntherng, Juthamas, Vliegen, Maarten, de Zwart, Loeckie, Mannaert, Erik, de Jong, Jan
Publié dans Br J Clin Pharmacol (2016)

Abiraterone Acetate to Lower Androgens in Women With Classic 21-Hydroxylase Deficiency

par Auchus, Richard J., Buschur, Elizabeth O., Chang, Alice Y., Hammer, Gary D., Ramm, Carole, Madrigal, David, Wang, George, Gonzalez, Martha, Xu, Xu Steven, Smit, Johan W., Jiao, James, Yu, Margaret K.
Publié 2014

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism

par van Herwaarden, Antonius E., Wagenaar, Els, van der Kruijssen, Cornelia M.M., van Waterschoot, Robert A.B., Smit, Johan W., Song, Ji-Ying, van der Valk, Martin A., van Tellingen, Olaf, van der Hoorn, José W.A., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
Publié 2007