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Abiraterone Acetate to Lower Androgens in Women With Classic 21-Hydroxylase Deficiency

CONTEXT: Chronic supraphysiological glucocorticoid therapy controls the androgen excess of 21-hydroxylase deficiency (21OHD) but contributes to the high prevalence of obesity, glucose intolerance, and reduced bone mass in these patients. Abiraterone acetate (AA) is a prodrug for abiraterone, a poten...

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Bibliographic Details
Main Authors: Auchus, Richard J., Buschur, Elizabeth O., Chang, Alice Y., Hammer, Gary D., Ramm, Carole, Madrigal, David, Wang, George, Gonzalez, Martha, Xu, Xu Steven, Smit, Johan W., Jiao, James, Yu, Margaret K.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121028/
https://ncbi.nlm.nih.gov/pubmed/24780050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1258
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