Abiraterone Acetate to Lower Androgens in Women With Classic 21-Hydroxylase Deficiency

CONTEXT: Chronic supraphysiological glucocorticoid therapy controls the androgen excess of 21-hydroxylase deficiency (21OHD) but contributes to the high prevalence of obesity, glucose intolerance, and reduced bone mass in these patients. Abiraterone acetate (AA) is a prodrug for abiraterone, a poten...

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Main Authors: Auchus, Richard J., Buschur, Elizabeth O., Chang, Alice Y., Hammer, Gary D., Ramm, Carole, Madrigal, David, Wang, George, Gonzalez, Martha, Xu, Xu Steven, Smit, Johan W., Jiao, James, Yu, Margaret K.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Endocrine Care
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121028/
https://ncbi.nlm.nih.gov/pubmed/24780050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1258
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