Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted

Por Smit, Johan W, Schinkel, Alfred H, Weert, Betty, Meijer, Dirk K F
Publicado em 1998

Crosslinked Poly(2-oxazoline)s as “Green” Materials for Electronic Applications

Por Fimberger, Martin, Tsekmes, Ioannis-Alexandros, Kochetov, Roman, Smit, Johan J., Wiesbrock, Frank
Publicado no Polymers (Basel) (2015)

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

Por Smit, Johan W., Huisman, Maarten T., van Tellingen, Olaf, Wiltshire, Hugh R., Schinkel, Alfred H.
Publicado em 1999

Interactions between P-glycoprotein substrates and other cationic drugs at the hepatic excretory level

Por Smit, Johan W, Duin, Erik, Steen, Herman, Oosting, Roelof, Roggeveld, Jan, Meijer, Dirk K F
Publicado em 1998

Effect of Interfacial Polarization and Water Absorption on the Dielectric Properties of Epoxy-Nanocomposites

Por Marx, Philipp, Wanner, Andrea J., Zhang, Zucong, Jin, Huifei, Tsekmes, Ioannis-Alexandros, Smit, Johan J., Kern, Wolfgang, Wiesbrock, Frank
Publicado no Polymers (Basel) (2017)

Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene

Por Jonker, Johan W., Wagenaar, Els, Mol, Carla A. A. M., Buitelaar, Marije, Koepsell, Hermann, Smit, Johan W., Schinkel, Alfred H.
Publicado em 2001

Effect of CYP3A perpetrators on ibrutinib exposure in healthy participants

Por de Jong, Jan, Skee, Donna, Murphy, Joe, Sukbuntherng, Juthamas, Hellemans, Peter, Smit, Johan, de Vries, Ronald, Jiao, Juhui James, Snoeys, Jan, Mannaert, Erik
Publicado no Pharmacol Res Perspect (2015)

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Por Sparreboom, Alex, van Asperen, Judith, Mayer, Ulrich, Schinkel, Alfred H., Smit, Johan W., Meijer, Dirk K. F., Borst, Piet, Nooijen, Willem J., Beijnen, Jos H., van Tellingen, Olaf
Publicado em 1997

Stable isotope‐labelled intravenous microdose for absolute bioavailability and effect of grapefruit juice on ibrutinib in healthy adults

Por de Vries, Ronald, Smit, Johan W., Hellemans, Peter, Jiao, James, Murphy, Joseph, Skee, Donna, Snoeys, Jan, Sukbuntherng, Juthamas, Vliegen, Maarten, de Zwart, Loeckie, Mannaert, Erik, de Jong, Jan
Publicado no Br J Clin Pharmacol (2016)

Abiraterone Acetate to Lower Androgens in Women With Classic 21-Hydroxylase Deficiency

Por Auchus, Richard J., Buschur, Elizabeth O., Chang, Alice Y., Hammer, Gary D., Ramm, Carole, Madrigal, David, Wang, George, Gonzalez, Martha, Xu, Xu Steven, Smit, Johan W., Jiao, James, Yu, Margaret K.
Publicado em 2014

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism

Por van Herwaarden, Antonius E., Wagenaar, Els, van der Kruijssen, Cornelia M.M., van Waterschoot, Robert A.B., Smit, Johan W., Song, Ji-Ying, van der Valk, Martin A., van Tellingen, Olaf, van der Hoorn, José W.A., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
Publicado em 2007