Functional Diversification of Paralogous Transcription Factors via Divergence in DNA Binding Site Motif and in Expression

Por Singh, Larry N., Hannenhalli, Sridhar
Publicado em 2008

Correlated changes between regulatory cis elements and condition-specific expression in paralogous gene families

Por Singh, Larry N., Hannenhalli, Sridhar
Publicado em 2010

TREMOR—a tool for retrieving transcriptional modules by incorporating motif covariance

Por Singh, Larry N., Wang, Li-San, Hannenhalli, Sridhar
Publicado em 2007

Correlated Evolution of Positions within Mammalian cis Elements

Por Mukherjee, Rithun, Evans, Perry, Singh, Larry N., Hannenhalli, Sridhar
Publicado em 2013

Assessing the reproducibility of exome copy number variations predictions

Por Hong, Celine S., Singh, Larry N., Mullikin, James C., Biesecker, Leslie G.
Publicado no Genome Med (2016)

CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features

Por Essien, Kobby, Vigneau, Sebastien, Apreleva, Sofia, Singh, Larry N, Bartolomei, Marisa S, Hannenhalli, Sridhar
Publicado em 2009

U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation

Por Kaida, Daisuke, Berg, Michael G., Younis, Ihab, Kasim, Mumtaz, Singh, Larry N., Wan, Lili, Dreyfuss, Gideon
Publicado em 2010

Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening

Por Ng, David, Hong, Celine S., Singh, Larry N., Johnston, Jennifer J., Mullikin, James C., Biesecker, Leslie G.
Publicado no Genet Med (2016)

A New Mouse Model of Mild Ornithine Transcarbamylase Deficiency (spf-j) Displays Cerebral Amino Acid Perturbations at Baseline and upon Systemic Immune Activation

Por Tarasenko, Tatyana N., Rosas, Odrick R., Singh, Larry N., Kristaponis, Kara, Vernon, Hilary, McGuire, Peter J.
Publicado no PLoS One (2015)

Secondary Variants in Individuals Undergoing Exome Sequencing: Screening of 572 Individuals Identifies High-Penetrance Mutations in Cancer-Susceptibility Genes

Por Johnston, Jennifer J., Rubinstein, Wendy S., Facio, Flavia M., Ng, David, Singh, Larry N., Teer, Jamie K., Mullikin, James C., Biesecker, Leslie G.
Publicado em 2012

Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy

Por Zhang, Zhenxi, Pinto, Anna Maria, Wan, Lili, Wang, Wei, Berg, Michael G., Oliva, Isabela, Singh, Larry N., Dengler, Christopher, Wei, Zhi, Dreyfuss, Gideon
Publicado em 2013

U1 snRNP Determines mRNA Length and Regulates Isoform Expression

Por Berg, Michael G., Singh, Larry N., Younis, Ihab, Liu, Qiang, Pinto, Anna Maria, Kaida, Daisuke, Zhang, Zhenxi, Cho, Sungchan, Sherrill-Mix, Scott, Wan, Lili, Dreyfuss, Gideon
Publicado em 2012

Interpreting Secondary Cardiac Disease Variants in an Exome Cohort

Por Ng, David, Johnston, Jennifer J., Teer, Jamie K., Singh, Larry N., Peller, Lindsey C., Wynter, Jamila S., Lewis, Katie L., Cooper, David N., Stenson, Peter D., Mullikin, James C., Biesecker, Leslie G.
Publicado em 2013

AKT1 gene mutation levels are correlated with the type of dermatologic lesions in patients with Proteus syndrome

Por Lindhurst, Marjorie J., Wang, Ji-an, Bloomhardt, Hadley M., Witkowski, Alison M., Singh, Larry N., Bick, David P., Gambello, Michael J., Powell, Cynthia M., Lee, Chyi-Chia Richard, Darling, Thomas N., Biesecker, Leslie G.
Publicado em 2013

Identification of candidate genes involved in coronary artery calcification by transcriptome sequencing of cell lines

Por Sen, Shurjo K, Barb, Jennifer J, Cherukuri, Praveen F, Accame, David S, Elkahloun, Abdel G, Singh, Larry N, Lee-Lin, Shih-Queen, Program, NISC Comparative Sequencing, Kolodgie, Frank D, Cheng, Qi, Zhao, XiaoQing, Chen, Marcus Y, Arai, Andrew E, Green, Eric D, Mullikin, James C, Munson, Peter J, Biesecker, Leslie G
Publicado em 2014

Individualized Iterative Phenotyping for Genome-wide Analysis of Loss-of-Function Mutations

Por Johnston, Jennifer J., Lewis, Katie L., Ng, David, Singh, Larry N., Wynter, Jamila, Brewer, Carmen, Brooks, Brian P., Brownell, Isaac, Candotti, Fabio, Gonsalves, Steven G., Hart, Suzanne P., Kong, Heidi H., Rother, Kristina I., Sokolic, Robert, Solomon, Benjamin D., Zein, Wadih M., Cooper, David N., Stenson, Peter D., Mullikin, James C., Biesecker, Leslie G.
Publicado no Am J Hum Genet (2015)

Integrative DNA, RNA, and Protein Evidence Connects TREML4 to Coronary Artery Calcification

Por Sen, Shurjo K., Boelte, Kimberly C., Barb, Jennifer J., Joehanes, Roby, Zhao, XiaoQing, Cheng, Qi, Adams, Lila, Teer, Jamie K., Accame, David S., Chowdhury, Soma, Singh, Larry N., Kavousi, Maryam, Peyser, Patricia A., Quigley, Laura, Priel, Debra Long, Lau, Karen, Kuhns, Douglas B., Yoshimura, Teizo, Johnson, Andrew D., Hwang, Shih-Jen, Chen, Marcus Y., Arai, Andrew E., Green, Eric D., Mullikin, James C., Kolodgie, Frank D., O’Donnell, Christopher J., Virmani, Renu, Munson, Peter J., McVicar, Daniel W., Biesecker, Leslie G.
Publicado em 2014