Pharmacy Practice and Education in the Czech Republic †

著者: Nachtigal, Petr, Šimůnek, Tomáš, Atkinson, Jeffrey
出版年 Pharmacy (Basel) (2017)

Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection

著者: Štěrba, Martin, Popelová, Olga, Vávrová, Anna, Jirkovský, Eduard, Kovaříková, Petra, Geršl, Vladimír, Šimůnek, Tomáš
出版事項 2013

Catalytic Inhibitors of Topoisomerase II Differently Modulate the Toxicity of Anthracyclines in Cardiac and Cancer Cells

著者: Vavrova, Anna, Jansova, Hana, Mackova, Eliska, Machacek, Miloslav, Haskova, Pavlina, Tichotova, Lucie, Sterba, Martin, Simunek, Tomas
出版事項 2013

UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study

著者: Reimerová, Petra, Jirkovská, Anna, Piskáčková, Hana Bavlovič, Karabanovich, Galina, Roh, Jaroslav, Šimůnek, Tomáš, Štěrbová-Kovaříková, Petra
出版年 Sci Rep (2019)

Molecular Remodeling of Left and Right Ventricular Myocardium in Chronic Anthracycline Cardiotoxicity and Post-Treatment Follow Up

著者: Lenčová-Popelová, Olga, Jirkovský, Eduard, Mazurová, Yvona, Lenčo, Juraj, Adamcová, Michaela, Šimůnek, Tomáš, Geršl, Vladimír, Štěrba, Martin
出版事項 2014

Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury

著者: Hašková, Pavlína, Jansová, Hana, Bureš, Jan, Macháček, Miloslav, Jirkovská, Anna, Franz, Katherine J., Kovaříková, Petra, Šimůnek, Tomáš
出版年 Toxicology (2016)

Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury

著者: Jansová, Hana, Macháček, Miloslav, Wang, Qin, Hašková, Pavlína, Jirkovská, Anna, Potůčková, Eliška, Kielar, Filip, Franz, Katherine J., Šimůnek, Tomáš
出版年 Free Radic Biol Med (2014)

Binding of an amphiphilic phthalocyanine to pre-formed liposomes confers light-triggered cargo release

著者: Macháček, Miloslav, Carter, Kevin A, Kostelanský, Filip, Miranda, Dyego, Seffouh, Amal, Ortega, Joaquin, Šimůnek, Tomáš, Zimčík, Petr, Lovell, Jonathan F
出版年 J Mater Chem B (2018)

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

著者: Potuckova, Eliska, Jansova, Hana, Machacek, Miloslav, Vavrova, Anna, Haskova, Pavlina, Tichotova, Lucie, Richardson, Vera, Kalinowski, Danuta S., Richardson, Des R., Simunek, Tomas
出版事項 2014

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products

著者: Jansová, Hana, Bureš, Jan, Macháček, Miloslav, Hašková, Pavlína, Jirkovská, Anna, Roh, Jaroslav, Wang, Qin, Franz, Katherine J., Kovaříková, Petra, Šimůnek, Tomáš
出版年 Toxicology (2016)

LC-UV/MS methods for the analysis of prochelator - boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)

著者: Bureš, Jan, Jansová, Hana, Stariat, Ján, Filipský, Tomáš, Mladěnka, Přemysl, Šimůnek, Tomáš, Kučera, Radim, Klimeš, Jiří, Wang, Qin, Franz, Katherine J., Kovaříková, Petra
出版年 J Pharm Biomed Anal (2014)

Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury

著者: Říha, Michal, Hašková, Pavlína, Martin, Jan, Filipský, Tomáš, Váňová, Kateřina, Vávrová, Jaroslava, Holečková, Magdalena, Homola, Pavel, Vítek, Libor, Palicka, Vladimír, Šimůnek, Tomáš, Mladěnka, Přemysl
出版年 Oxid Med Cell Longev (2016)

Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress

著者: Filipský, Tomáš, Říha, Michal, Hašková, Pavlína, Pilařová, Veronika, Nováková, Lucie, Semecký, Vladimír, Vávrová, Jaroslava, Holečková, Magdaléna, Palicka, Vladimir, Šimůnek, Tomáš, Hrdina, Radomír, Mladěnka, Přemysl
出版年 Redox Rep (2016)

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

著者: Potůčková, Eliška, Roh, Jaroslav, Macháček, Miloslav, Sahni, Sumit, Stariat, Ján, Šesták, Vít, Jansová, Hana, Hašková, Pavlína, Jirkovská, Anna, Vávrová, Kateřina, Kovaříková, Petra, Kalinowski, Danuta S., Richardson, Des R., Šimůnek, Tomáš
出版年 PLoS One (2015)

Exploring the Anti-Cancer Activity of Novel Thiosemicarbazones Generated through the Combination of Retro-Fragments: Dissection of Critical Structure-Activity Relationships

著者: Serda, Maciej, Kalinowski, Danuta S., Rasko, Nathalie, Potůčková, Eliška, Mrozek-Wilczkiewicz, Anna, Musiol, Robert, Małecki, Jan G., Sajewicz, Mieczysław, Ratuszna, Alicja, Muchowicz, Angelika, Gołąb, Jakub, Šimůnek, Tomáš, Richardson, Des R., Polanski, Jaroslaw
出版事項 2014

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead ag...

著者: Sestak, Vit, Stariat, Jan, Cermanova, Jolana, Potuckova, Eliska, Chladek, Jaroslav, Roh, Jaroslav, Bures, Jan, Jansova, Hana, Prusa, Petr, Sterba, Martin, Micuda, Stanislav, Simunek, Tomas, Kalinowski, Danuta S., Richardson, Des R., Kovarikova, Petra
出版年 Oncotarget (2015)

Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity

著者: Bavlovič Piskáčková, Hana, Jansová, Hana, Kubeš, Jan, Karabanovich, Galina, Váňová, Nela, Kollárová-Brázdová, Petra, Melnikova, Iuliia, Jirkovská, Anna, Lenčová-Popelová, Olga, Chládek, Jaroslav, Roh, Jaroslav, Šimůnek, Tomáš, Štěrba, Martin, Štěrbová-Kovaříková, Petra
出版年 Sci Rep (2021)

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties

著者: Potůčková, Eliška, Hrušková, Kateřina, Bureš, Jan, Kovaříková, Petra, Špirková, Iva A., Pravdíková, Kateřina, Kolbabová, Lucie, Hergeselová, Tereza, Hašková, Pavlína, Jansová, Hana, Macháček, Miloslav, Jirkovská, Anna, Richardson, Vera, Lane, Darius J. R., Kalinowski, Danuta S., Richardson, Des R., Vávrová, Kateřina, Šimůnek, Tomáš
出版年 PLoS One (2014)