Novel Insights into Molecular Indicators of Response and Resistance to Modern Androgen-Axis Therapies in Prostate Cancer

Por Silberstein, John L., Taylor, Maritza N., Antonarakis, Emmanuel S.
Publicado no Curr Urol Rep (2016)

Clinical Utility of CLIA-Grade AR-V7 Testing in Patients With Metastatic Castration-Resistant Prostate Cancer

Por Markowski, Mark C., Silberstein, John L., Eshleman, James R., Eisenberger, Mario A., Luo, Jun, Antonarakis, Emmanuel S.
Publicado no JCO Precis Oncol (2017)

Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer

Por Velho, Pedro Isaacsson, Silberstein, John L., Markowski, Mark C., Luo, Jun, Lotan, Tamara L., Isaacs, William B., Antonarakis, Emmanuel S.
Publicado no Prostate (2018)

Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide

Por Antonarakis, Emmanuel S., Lu, Changxue, Luber, Brandon, Liang, Chao, Wang, Hao, Chen, Yan, Silberstein, John L., Piana, Danilo, Lai, Zhao, Chen, Yidong, Isaacs, William B., Luo, Jun
Publicado no Eur Urol (2018)

Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First...

Por Antonarakis, Emmanuel S., Lu, Changxue, Luber, Brandon, Wang, Hao, Chen, Yan, Zhu, Yezi, Silberstein, John L., Taylor, Maritza N., Maughan, Benjamin L., Denmeade, Samuel R., Pienta, Kenneth J., Paller, Channing J., Carducci, Michael A., Eisenberger, Mario A., Luo, Jun
Publicado no J Clin Oncol (2017)

Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study

Por Teply, Benjamin A, Wang, Hao, Luber, Brandon, Sullivan, Rana, Rifkind, Irina, Bruns, Ashley, Spitz, Avery, DeCarli, Morgan, Sinibaldi, Victoria, Pratz, Caroline F, Lu, Changxue, Silberstein, John L, Luo, Jun, Schweizer, Michael T, Drake, Charles G, Carducci, Michael A, Paller, Channing J, Antonarakis, Emmanuel S, Eisenberger, Mario A, Denmeade, Samuel R
Publicado no Lancet Oncol (2017)

Detection fidelity of AR mutations in plasma derived cell-free DNA

Por Goldstein, Alexa, Toro, Patricia Valda, Lee, Justin, Silberstein, John L., Nakazawa, Mary, Waters, Ian, Cravero, Karen, Chu, David, Cochran, Rory L., Kim, Minsoo, Shinn, Daniel, Torquato, Samantha, Hughes, Robert M., Pallavajjala, Aparna, Carducci, Michael A., Paller, Channing J., Denmeade, Samuel R., Kressel, Bruce, Trock, Bruce J., Eisenberger, Mario A., Antonarakis, Emmanuel S., Park, Ben H., Hurley, Paula J.
Publicado no Oncotarget (2017)

Genetic Alterations Detected in Cell-Free DNA Are Associated With Enzalutamide and Abiraterone Resistance in Castration-Resistant Prostate Cancer

Por Torquato, Samantha, Pallavajjala, Aparna, Goldstein, Alexa, Valda Toro, Patricia, Silberstein, John L., Lee, Justin, Nakazawa, Mary, Waters, Ian, Chu, David, Shinn, Daniel, Groginski, Taylor, Hughes, Robert M., Simons, Brian W., Khan, Hamda, Feng, Zhaoyong, Carducci, Michael A., Paller, Channing J., Denmeade, Samuel R., Kressel, Bruce, Eisenberger, Mario A., Antonarakis, Emmanuel S., Trock, Bruce J., Park, Ben H., Hurley, Paula J.
Publicado no JCO Precis Oncol (2019)

Novel Junction-specific and Quantifiable In Situ Detection of AR-V7 and its Clinical Correlates in Metastatic Castration-resistant Prostate Cancer

Por Zhu, Yezi, Sharp, Adam, Anderson, Courtney M., Silberstein, John L., Taylor, Maritza, Lu, Changxue, Zhao, Pei, De Marzo, Angelo M., Antonarakis, Emmanuel S., Wang, Mindy, Wu, Xingyong, Luo, Yuling, Su, Nan, Rodrigues, Daniel Nava, Figueiredo, Ines, Welti, Jonathan, Park, Emily, Ma, Xiao-Jun, Coleman, Ilsa, Morrissey, Colm, Plymate, Stephen R., Nelson, Peter S., de Bono, Johann S., Luo, Jun
Publicado no Eur Urol (2017)

Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study

Por Armstrong, Andrew J., Halabi, Susan, Luo, Jun, Nanus, David M., Giannakakou, Paraskevi, Szmulewitz, Russell Z., Danila, Daniel C., Healy, Patrick, Anand, Monika, Rothwell, Colin J., Rasmussen, Julia, Thornburg, Blair, Berry, William R., Wilder, Rhonda S., Lu, Changxue, Chen, Yan, Silberstein, John L., Kemeny, Gabor, Galletti, Giuseppe, Somarelli, Jason A., Gupta, Santosh, Gregory, Simon G., Scher, Howard I., Dittamore, Ryan, Tagawa, Scott T., Antonarakis, Emmanuel S., George, Daniel J.
Publicado no J Clin Oncol (2019)

Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer

Por Boudadi, Karim, Suzman, Daniel L., Anagnostou, Valsamo, Fu, Wei, Luber, Brandon, Wang, Hao, Niknafs, Noushin, White, James R., Silberstein, John L., Sullivan, Rana, Dowling, Donna, Harb, Rana, Nirschl, Thomas R., Veeneman, Brendan A., Tomlins, Scott A., Wang, Yipeng, Jendrisak, Adam, Graf, Ryon P., Dittamore, Ryan, Carducci, Michael A., Eisenberger, Mario A., Haffner, Michael C., Meeker, Alan K., Eshleman, James R., Luo, Jun, Velculescu, Victor E., Drake, Charles G., Antonarakis, Emmanuel S.
Publicado no Oncotarget (2018)