Novel Junction-specific and Quantifiable In Situ Detection of AR-V7 and its Clinical Correlates in Metastatic Castration-resistant Prostate Cancer

BACKGROUND: Androgen receptor splice variant 7 (AR-V7) has been implicated in resistance to abiraterone and enzalutamide treatment in men with metastatic castrationresistant prostate cancer (mCRPC). Tissue- or cell-based in situ detection of AR-V7, however, has been limited by lack of specificity. O...

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Pubblicato in:Eur Urol
Autori principali: Zhu, Yezi, Sharp, Adam, Anderson, Courtney M., Silberstein, John L., Taylor, Maritza, Lu, Changxue, Zhao, Pei, De Marzo, Angelo M., Antonarakis, Emmanuel S., Wang, Mindy, Wu, Xingyong, Luo, Yuling, Su, Nan, Rodrigues, Daniel Nava, Figueiredo, Ines, Welti, Jonathan, Park, Emily, Ma, Xiao-Jun, Coleman, Ilsa, Morrissey, Colm, Plymate, Stephen R., Nelson, Peter S., de Bono, Johann S., Luo, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538073/
https://ncbi.nlm.nih.gov/pubmed/28866255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2017.08.009
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