Clinical Utility of CLIA-Grade AR-V7 Testing in Patients With Metastatic Castration-Resistant Prostate Cancer

PURPOSE: A splice variant of the androgen receptor, AR-V7, confers resistance to AR-targeted therapies (ATTs) but not taxane chemotherapies in patients with metastatic castration-resistant prostate cancer. Since August 2015, a clinical-grade assay to detect AR-V7 messenger RNA expression in circulat...

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Detalhes bibliográficos
Publicado no:JCO Precis Oncol
Main Authors: Markowski, Mark C., Silberstein, John L., Eshleman, James R., Eisenberger, Mario A., Luo, Jun, Antonarakis, Emmanuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697780/
https://ncbi.nlm.nih.gov/pubmed/29170762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00127
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