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Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer

BACKGROUND: Germline mutations in genes mediating DNA repair are common in men with recurrent and advanced prostate cancer, and their presence may alter prognosis and management. We aimed to define pathological and clinical characteristics associated with germline DNA-repair gene mutations, to facil...

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Detalhes bibliográficos
Publicado no:Prostate
Main Authors: Velho, Pedro Isaacsson, Silberstein, John L., Markowski, Mark C., Luo, Jun, Lotan, Tamara L., Isaacs, William B., Antonarakis, Emmanuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524639/
https://ncbi.nlm.nih.gov/pubmed/29368341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23484
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