Meeting the unique challenges of drug discovery for neurodegenerative diseases

Por Shineman, Diana W, Fillit, Howard M
Publicado em 2009

Novel strategies for the prevention of dementia from Alzheimer's disease

Por Shineman, Diana W., Fillit, Howard M
Publicado em 2009

A diverse portfolio of novel drug discovery efforts for Alzheimer's disease: Meeting report from the 11th International Conference on Alzheimer's Drug Discovery, 27-28 September 20...

Por Lee, Linda H, Shineman, Diana W, Fillit, Howard M
Publicado em 2010

Beyond amyloid: a diverse portfolio of novel drug discovery programs for Alzheimer's disease and related dementias

Por Lane, Rachel F, Shineman, Diana W, Fillit, Howard M
Publicado em 2011

Constitutively Active Akt Inhibits Trafficking of Amyloid Precursor Protein and Amyloid Precursor Protein Metabolites through Feedback Inhibition of Phosphoinositide 3-Kinase

Por Shineman, Diana W., Dain, Aleksandra S., Kim, Minkyu L., Lee, Virginia M.-Y.
Publicado em 2009

Diverse therapeutic targets and biomarkers for Alzheimer's disease and related dementias: report on the Alzheimer's Drug Discovery Foundation 2012 International Conference on Alzhe...

Por Lane, Rachel F, Dacks, Penny A, Shineman, Diana W, Fillit, Howard M
Publicado em 2013

Progress in novel cognitive enhancers for cognitive aging and Alzheimer’s disease

Por Shineman, Diana W, Carman, Aaron J, Dacks, Penny A, Lane, Rachel F, Fillit, Howard M
Publicado em 2013

Meeting report on the Alzheimer’s Drug Discovery Foundation 14th International Conference on Alzheimer’s Drug Discovery

Por Friedman, Lauren G, Price, Katherine, Lane, Rachel F, Carman, Aaron J, Dacks, Penny A, Shineman, Diana W, Fillit, Howard M
Publicado em 2014

Modulation of Nuclear Factor-κB Activity by Indomethacin Influences Aβ Levels but Not Aβ Precursor Protein Metabolism in a Model of Alzheimer’s Disease

Por Sung, Syaun, Yang, Hengxuan, Uryu, Kunihiro, Lee, Edward B., Zhao, Lei, Shineman, Diana, Trojanowski, John Q., Lee, Virginia M.-Y., Praticò, Domenico
Publicado em 2004

Mechanism of Ca(2+) Disruption in Alzheimer’s Disease by Presenilin Regulation of InsP(3) Receptor Channel Gating

Por Cheung, King-Ho, Shineman, Diana, Muller, Marioly, Cardenas, Cesar, Mei, Lijuan, Yang, Jun, Tomita, Taisuke, Iwatsubo, Takeshi, Lee, Virginia M.-Y., Foskett, J. Kevin
Publicado em 2008

Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size

Por Easton, Rachael M., Cho, Han, Roovers, Kristin, Shineman, Diana W., Mizrahi, Moshe, Forman, Mark S., Lee, Virginia M.-Y., Szabolcs, Matthias, de Jong, Ron, Oltersdorf, Tilman, Ludwig, Thomas, Efstratiadis, Argiris, Birnbaum, Morris J.
Publicado em 2005

Therapeutics for cognitive aging

Por Shineman, Diana W., Salthouse, Timothy A., Launer, Lenore J., Hof, Patrick R., Bartzokis, George, Kleiman, Robin, Luine, Victoria, Buccafusco, Jerry J., Small, Gary W., Aisen, Paul S., Lowe, David A., Fillit, Howard M.
Publicado em 2010

Overcoming obstacles to repurposing for neurodegenerative disease

Por Shineman, Diana W, Alam, John, Anderson, Margaret, Black, Sandra E, Carman, Aaron J, Cummings, Jeffrey L, Dacks, Penny A, Dudley, Joel T, Frail, Donald E, Green, Allan, Lane, Rachel F, Lappin, Debra, Simuni, Tanya, Stefanacci, Richard G, Sherer, Todd, Fillit, Howard M
Publicado em 2014

Exploring the Nexus of Alzheimer’s Disease and Related Dementias with Cancer and Cancer Therapies

Por Snyder, Heather M., Ahles, Timothy, Calderwood, Stuart, Carrillo, Maria C., Chen, Honglei, Chang, Chung-Chou, Craft, Suzanne, De Jager, Philip, Driver, Jane A., Fillet, Howard, Knopman, David, Lotze, Michael, Tierney, Mary C., Petanceska, Suzana, Saykin, Andrew, Seshadri, Sudha, Shineman, Diana, Ganguli, Mary
Publicado no Alzheimers Dement (2016)

Developing Novel Blood-Based Biomarkers for Alzheimer's Disease

Por Snyder, Heather M., Carrillo, Maria C., Grodstein, Francine, Henriksen, Kim, Jeromin, Andreas, Lovestone, Simon, Mielke, Michelle M., O’Bryant, Sid, Sarasa, Manual, Sjøgren, Magnus, Soares, Holly, Teeling, Jessica, Trushina, Eugenia, Ward, Malcolm, West, Tim, Bain, Lisa J., Shineman, Diana W., Weiner, Michael, Fillit, Howard M.
Publicado no Alzheimers Dement (2014)

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

Por Shineman, Diana W, Basi, Guriqbal S, Bizon, Jennifer L, Colton, Carol A, Greenberg, Barry D, Hollister, Beth A, Lincecum, John, Leblanc, Gabrielle G, Lee, Linda (Bobbi) H, Luo, Feng, Morgan, Dave, Morse, Iva, Refolo, Lorenzo M, Riddell, David R, Scearce-Levie, Kimberly, Sweeney, Patrick, Yrjänheikki, Juha, Fillit, Howard M
Publicado em 2011

Dementia Prevention: optimizing the use of observational data for personal, clinical, and public health decision-making

Por Dacks, Penny A, Andrieu, Sandrine, Blacker, Deborah, Carman, Aaron J, Green, Allan M, Grodstein, Francine, Henderson, Victor W, James, Bryan D., Lane, Rachel F, Lau, Joseph, Lin, Pei-Jung, Reeves, Barnaby C., Shah, Raj C., Vellas, Bruno, Yaffe, Kristine, Yurko-Mauro, Karin, Shineman, Diana W, Bennett, David A, Fillit, Howard M
Publicado no J Prev Alzheimers Dis (2014)

A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline

Por Dacks, Penny A., Armstrong, Joshua J., Brannan, Stephen K., Carman, Aaron J., Green, Allan M., Kirkman, M. Sue, Krakoff, Lawrence R., Kuller, Lewis H., Launer, Lenore J., Lovestone, Simon, Merikle, Elizabeth, Neumann, Peter J., Rockwood, Kenneth, Shineman, Diana W., Stefanacci, Richard G., Velentgas, Priscilla, Viswanathan, Anand, Whitmer, Rachel A., Williamson, Jeff D., Fillit, Howard M.
Publicado no Alzheimers Res Ther (2016)