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Beyond amyloid: a diverse portfolio of novel drug discovery programs for Alzheimer's disease and related dementias
Although the molecular mechanisms underlying the pathogenesis of Alzheimer's disease and other related neurodegenerative diseases remain unclear, accumulation of misfolded proteins, neuroinflammation, mitochondrial dysfunction and perturbed calcium homeostasis have been identified as key events...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308025/ https://ncbi.nlm.nih.gov/pubmed/22236739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt99 |
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