Novel high throughput screen identifies an HIV-1 reverse transcriptase inhibitor with a unique mechanism of action

Por Sheen, Chih-Wei, Alptürk, Onur, Sluis-Cremer, Nicolas
Publicado no Biochem J (2014)

Mechanisms by Which the G333D Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Facilitates Dual Resistance to Zidovudine and Lamivudine

Por Zelina, Shannon, Sheen, Chih-Wei, Radzio, Jessica, Mellors, John W., Sluis-Cremer, Nicolas
Publicado em 2008

Molecular Mechanism by Which the K70E Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Resistance to Nucleoside Reverse Transcriptase Inhibitors

Por Sluis-Cremer, Nicolas, Sheen, Chih-Wei, Zelina, Shannon, Torres, Pedro S. Argoti, Parikh, Urvi M., Mellors, John W.
Publicado em 2007

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT

Por Nissley, Dwight V., Radzio, Jessica, Ambrose, Zandrea, Sheen, Chih-Wei, Hamamouch, Noureddine, Moore, Katie L., Tachedjian, Gilda, Sluis-Cremer, Nicolas
Publicado em 2007

The Human Immunodeficiency Virus Type 1 Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation I132M Confers Hypersensitivity to Nucleoside Analogs

Por Ambrose, Zandrea, Herman, Brian D., Sheen, Chih-Wei, Zelina, Shannon, Moore, Katie L., Tachedjian, Gilda, Nissley, Dwight V., Sluis-Cremer, Nicolas
Publicado em 2009

Silent Mutations are Selected in HIV-1 Reverse Transcriptase and Affect Enzymatic Efficiency

Por Harrigan, P. Richard, Sheen, Chih-Wei, Gill, Vikram S., Wynhoven, Brian, Hudson, Erin, Lima, Viviane D., Lecocq, Pierre, Aguirre, Rosalia, Poon, Art F.Y., Sluis-Cremer, Nicolas
Publicado no AIDS (2008)

N348I in the Connection Domain of HIV-1 Reverse Transcriptase Confers Zidovudine and Nevirapine Resistance

Por Yap, Soo-Huey, Sheen, Chih-Wei, Fahey, Jonathan, Zanin, Mark, Tyssen, David, Lima, Viviane Dias, Wynhoven, Brian, Kuiper, Michael, Sluis-Cremer, Nicolas, Harrigan, P. Richard, Tachedjian, Gilda
Publicado em 2007