Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response

Por Sheedy, Frederick J.
Publicado no Front Immunol (2015)

miR-21 alters circulating Treg function in vascular disease—hope for restoring immunoregulatory responses in atherosclerosis?

Por Hackett, Emer E., Sheedy, Frederick J.
Publicado no Ann Transl Med (2017)

Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6

Por Hennessy, Elizabeth J., Sheedy, Frederick J., Santamaria, David, Barbacid, Mariano, O'Neill, Luke A. J.
Publicado em 2011

IL-10 Inhibits miR-155 Induction by Toll-like Receptors

Por McCoy, Claire E., Sheedy, Frederick J., Qualls, Joseph E., Doyle, Sarah L., Quinn, Susan R., Murray, Peter J., O'Neill, Luke A. J.
Publicado em 2010

Netrin-1 promotes adipose tissue macrophage accumulation and insulin resistance in obesity

Por Ramkhelawon, Bhama, Hennessy, Elizabeth J, Ménager, Mickaël, Ray, Tathagat Dutta, Sheedy, Frederick J, Hutchison, Susan, Wanschel, Amarylis, Oldebeken, Scott, Geoffrion, Michele, Spiro, Westley, Miller, George, McPherson, Ruth, Rayner, Katey J, Moore, Kathryn J
Publicado em 2014

CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation

Por Sheedy, Frederick J., Grebe, Alena, Rayner, Katey J., Kalantari, Parisa, Ramkhelawon, Bhama, Carpenter, Susan B., Becker, Christine E., Ediriweera, Hasini N., Mullick, Adam E., Golenbock, Douglas T., Stuart, Lynda M., Latz, Eicke, Fitzgerald, Katherine A., Moore, Kathryn J.
Publicado em 2013

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

Por Rayner, Katey J., Sheedy, Frederick J., Esau, Christine C., Hussain, Farah N., Temel, Ryan E., Parathath, Saj, van Gils, Janine M., Rayner, Alistair J., Chang, Aaron N., Suarez, Yajaira, Fernandez-Hernando, Carlos, Fisher, Edward A., Moore, Kathryn J.
Publicado em 2011

Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism

Por Ouimet, Mireille, Koster, Stefan, Sakowski, Erik, Ramkhelawon, Bhama, van Solingen, Coen, Oldebeken, Scott, Karunakaran, Denuja, Celhay, Cynthia Portal, Sheedy, Frederick J., Ray, Tathagat Dutta, Cecchini, Katharine, Zamore, Philip D, Rayner, Katey J, Marcel, Yves L, Philips, Jennifer A, Moore, Kathryn J
Publicado no Nat Immunol (2016)

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

Por Ouimet, Mireille, Ediriweera, Hasini N., Gundra, U. Mahesh, Sheedy, Frederick J., Ramkhelawon, Bhama, Hutchison, Susan B., Rinehold, Kaitlyn, van Solingen, Coen, Fullerton, Morgan D., Cecchini, Katharine, Rayner, Katey J., Steinberg, Gregory R., Zamore, Phillip D., Fisher, Edward A., Loke, P’ng, Moore, Kathryn J.
Publicado no J Clin Invest (2015)

Inhibition of miR-33a/b in non-human primates raises plasma HDL and reduces VLDL triglycerides

Por Rayner, Katey J., Esau, Christine C., Hussain, Farah N., McDaniel, Allison L., Marshall, Stephanie M., van Gils, Janine M., Ray, Tathagat D., Sheedy, Frederick J., Goedeke, Leigh, Liu, Xueqing, Khatsenko, Oleg G., Kaimal, Vivek, Lees, Cynthia J., Fernandez-Hernando, Carlos, Fisher, Edward A., Temel, Ryan E., Moore, Kathryn J.
Publicado em 2011

Pyruvate Kinase M2 regulates Hif-1α activity and IL-1β induction, and is a critical determinant of the Warburg Effect in LPS-activated macrophages

Por Palsson-McDermott, Eva M, Curtis, Anne M, Goel, Gautam, Lauterbach, Mario AR, Sheedy, Frederick J, Gleeson, Laura E, van den Bosch, Mirjam WM, Quinn, Susan R, Domingo-Fernandez, Raquel, Johnson, Daniel GW, Jiang, Jain-kang, Israelsen, William J., Keane, Joseph, Thomas, Craig, Clish, Clary, Heiden, Matthew Vanden, Xavier, Ramnik J, O’Neill, Luke A.J.
Publicado no Cell Metab (2015)

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling

Por Ní Cheallaigh, Clíona, Sheedy, Frederick J., Harris, James, Muñoz-Wolf, Natalia, Lee, Jinhee, West, Kim, McDermott, Eva Palsson, Smyth, Alicia, Gleeson, Laura E., Coleman, Michelle, Martinez, Nuria, Hearnden, Claire H.A., Tynan, Graham A., Carroll, Elizabeth C., Jones, Sarah A., Corr, Sinéad C., Bernard, Nicholas J., Hughes, Mark M., Corcoran, Sarah E., O’Sullivan, Mary, Fallon, Ciara M., Kornfeld, Hardy, Golenbock, Douglas, Gordon, Stephen V., O’Neill, Luke A.J., Lavelle, Ed C., Keane, Joseph
Publicado no Immunity (2016)