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Netrin-1 promotes adipose tissue macrophage accumulation and insulin resistance in obesity
During obesity, macrophage accumulation in adipose tissue propagates the chronic inflammation and insulin resistance associated with type 2 diabetes. The factors that regulate the accrual of macrophages in adipose are not well understood. Here we show that the neuroimmune guidance cue netrin-1 is hi...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3981930/ https://ncbi.nlm.nih.gov/pubmed/24584118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3467 |
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