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Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: a mechanism for macrophage retention and survival

OBJECTIVE: Hypoxia is intimately linked to atherosclerosis and has become recognized as a primary impetus of inflammation. We recently demonstrated that the neuroimmune guidance cue, netrin-1 (Ntn1) inhibits macrophage emigration from atherosclerotic plaques thereby fostering chronic inflammation. H...

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Hlavní autoři: Ramkhelawon, Bhama, Yang, Yuan, van Gils, Janine M, Hewing, Bernd, Rayner, Katey J, Parathath, Sajesh, Guo, Liang, Oldebeken, Scott, Feig, Jessica L, Fisher, Edward A, Moore, Kathryn J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793633/
https://ncbi.nlm.nih.gov/pubmed/23599441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301008
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