Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: a mechanism for macrophage retention and survival

OBJECTIVE: Hypoxia is intimately linked to atherosclerosis and has become recognized as a primary impetus of inflammation. We recently demonstrated that the neuroimmune guidance cue, netrin-1 (Ntn1) inhibits macrophage emigration from atherosclerotic plaques thereby fostering chronic inflammation. H...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ramkhelawon, Bhama, Yang, Yuan, van Gils, Janine M, Hewing, Bernd, Rayner, Katey J, Parathath, Sajesh, Guo, Liang, Oldebeken, Scott, Feig, Jessica L, Fisher, Edward A, Moore, Kathryn J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793633/
https://ncbi.nlm.nih.gov/pubmed/23599441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301008
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