The long-awaited demonstration of protein pyrophosphorylation by IP7 in vivo?

Por Shears, Stephen
Publicado em 2010

Telomere maintenance by intracellular signals: New kid on the block?

Por Shears, Stephen B.
Publicado em 2005

How versatile are inositol phosphate kinases?

Por Shears, Stephen B
Publicado em 2004

Diphosphoinositol Polyphosphates: Metabolic Messengers?

Por Shears, Stephen B.
Publicado em 2009

Inositol pyrophosphates: why so many phosphates?

Por Shears, Stephen B.
Publicado no Adv Biol Regul (2014)

Molecular basis for the integration of inositol phosphate signaling pathways via human ITPK1

Por Shears, Stephen B.
Publicado no Adv Enzyme Regul (2009)

Intimate connections: Inositol pyrophosphates at the interface of metabolic regulation and cell signaling

Por Shears, Stephen B.
Publicado no J Cell Physiol (2017)

Towards pharmacological intervention in inositol pyrophosphate signalling

Por Shears, Stephen B.
Publicado no Biochem Soc Trans (2016)

Structural features of human inositol phosphate multikinase rationalize its inositol phosphate kinase and phosphoinositide 3-kinase activities

Por Wang, Huanchen, Shears, Stephen B.
Publicado no J Biol Chem (2017)

The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment

Por Weaver, Jeremy D., Wang, Huanchen, Shears, Stephen B.
Publicado em 2013

Structural insight into inositol pyrophosphate turnover

Por Shears, Stephen B., Weaver, Jeremy D., Wang, Huanchen
Publicado em 2012

Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain

Por Gokhale, Nikhil A., Zaremba, Angelika, Shears, Stephen B.
Publicado em 2011

Pathogenicity of Salmonella: SopE-mediated membrane ruffling is independent of inositol phosphate signals

Por Deleu, Sandrine, Choi, Kuicheon, Reece, Jeff M., Shears, Stephen B.
Publicado em 2006

Cellular Energetic Status Supervises the Synthesis of Bis-Diphosphoinositol Tetrakisphosphate Independently of AMP-Activated Protein Kinase

Por Choi, Kuicheon, Mollapour, Elahe, Choi, Jae H., Shears, Stephen B.
Publicado em 2008

Diphosphoinositol Polyphosphates: What are the Mechanisms?

Por Shears, Stephen B, Gokhale, Nikhil A., Wang, Huanchen, Zaremba, Angelika
Publicado em 2010

Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs

Por Kilari, Rajagopal S., Weaver, Jeremy D., Shears, Stephen B., Safrany, Stephen T.
Publicado em 2013

Metabolic and Signaling Properties of an Itpk Gene Family in Glycine max

Por Stiles, Amanda R., Qian, Xun, Shears, Stephen B., Grabau, Elizabeth A.
Publicado em 2008

Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport–Luebering glycolytic shunt

Por Cho, Jaiesoon, King, Jason S., Qian, Xun, Harwood, Adrian J., Shears, Stephen B.
Publicado em 2008

Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding

Por Wang, Huanchen, Falck, J R, Hall, Traci M Tanaka, Shears, Stephen B
Publicado em 2011

Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation

Por Capolicchio, Samanta, Wang, Huanchen, Thakor, Divyeshsinh T., Shears, Stephen B., Jessen, Henning J.
Publicado em 2014