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Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain

The inositol pyrophosphates are multifunctional signalling molecules. One of the families of enzymes that synthesize the inositol pyrophosphates are the Vip1/PPIP5Ks (PP-InsP(5) kinases). The kinase domains in Vip1/PPIP5Ks have been mapped to their N-terminus. Each of these proteins also possess a p...

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Autori principali: Gokhale, Nikhil A., Zaremba, Angelika, Shears, Stephen B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962999/
https://ncbi.nlm.nih.gov/pubmed/21222653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101437
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