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Dynamics of substrate processing by PPIP5K2, a versatile catalytic machine

Processing of substrates by enzymes can only be fully understood through their conformational dynamics; that is particularly true for the diphosphoinositol pentakisphosphate kinase PPIP5K2, an enzyme with critical roles in cell signaling and bioenergetic homestasis. PPIP5K2 is remarkable for the rev...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: An, Yi, Jessen, Henning J., Wang, Huanchen, Shears, Stephen B., Kireev, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551306/
https://ncbi.nlm.nih.gov/pubmed/30956131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.03.007
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