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PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P(3) for polyphosphoinositide-binding domains
We describe new signalling consequences for PPIP5K1 (diphosphoinositol pentakisphosphate kinase type 1)-mediated phosphorylation of InsP(6) and 5-InsP(7) to 1-InsP(7) and InsP(8). In NIH 3T3 cells, either hyperosmotic stress or receptor activation by PDGF (platelet-derived growth factor) promoted tr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931004/ https://ncbi.nlm.nih.gov/pubmed/23682967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121528 |
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