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Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation
The ubiquitous mammalian signaling molecule bisdiphosphoinositol tetrakisphosphate (1,5-(PP)(2)-myo-InsP(4), or InsP(8)) displays the most congested three-dimensional array of phosphate groups found in nature. The high charge density, the accumulation of unstable P-anhydrides and P-esters, the lack...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153399/ https://ncbi.nlm.nih.gov/pubmed/25044992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201404398 |
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