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Asp1 from Schizosaccharomyces pombe Binds a [2Fe-2S](2+) Cluster Which Inhibits Inositol Pyrophosphate 1-Phosphatase Activity

Iron-sulfur (Fe-S) clusters are widely distributed protein cofactors that are vital to cellular biochemistry and the maintenance of bioenergetic homeostasis, but to our knowledge, they have never been identified in any phosphatase. Here, we describe an iron–sulfur cluster in Asp1, a dual-function ki...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Wang, Huanchen, Nair, Vasudha S., Holland, Ashley A., Capolicchio, Samanta, Jessen, Henning J., Johnson, Michael K., Shears, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641441/
https://ncbi.nlm.nih.gov/pubmed/26422458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00532
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